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Mashup Score: 0On manels and manferences in urology - Nature Reviews Urology - 3 year(s) ago
Balancing diversity on panels at academic medical conferences demonstrates a commitment to the principles of diversity and inclusion. However, it seems we have a long way to go in urology, where two-thirds of sessions at major urology meetings still consist of all-male speaker panels.
Source: Nature Reviews UrologyCategories: Latest Headlines, UrologyTweet
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Mashup Score: 2Incorporating palliative care principles to improve patient care and quality of life in urologic oncology - Nature Reviews Urology - 3 year(s) ago
Society guidelines recommend incorporating palliative care into standard oncological care. However, misconceptions regarding palliative care are common — notably, palliative care and treatments seeking to cure or prolong life are not mutually exclusive. In this article, the authors discuss the integration of palliative care into surgical urologic oncology and consider palliative care guidelines,…
Source: Nature Reviews UrologyCategories: Latest Headlines, UrologyTweet-
#NEWinNRU a Perspective on incorporating palliative care principles to improve patient care and quality of life in urological oncology from @lhugar Elizabeth M. Wulff-Burchfield, @garywinz Bruce L. Jacobs & @daviesbj https://t.co/pJNP0rQsie https://t.co/LeIrnj9Abl
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Mashup Score: 5
Chimeric antigen receptor T cell immunotherapy for prostate cancer has the potential to be combined with other treatment modalities, such as androgen deprivation therapy, radiotherapy or chemotherapy; furthermore, new developments could improve the efficacy of chimeric antigen receptor T cell therapy and this treatment could also be applied as focal therapy for this disease.
Source: Nature Reviews UrologyCategories: Latest Headlines, UrologyTweet-
#ICYMI Review: The potential of CAR T cell therapy for #ProstateCancer by Philipp Wolf, Jamal Alzubi @cgratzke & Toni Cathomen https://t.co/1kX4YFB3TK https://t.co/dlixlR5Ipn
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Mashup Score: 2
The treatment of patients with the PD1 inhibitor pembrolizumab yields benefit in the second-line metastatic urothelial cancer setting. Two new trials have studied pembrolizumab monotherapy in other patients with urothelial carcinoma: an open-label phase II trial has enrolled patients with high-risk BCG-refractory non-muscle-invasive disease, and a phase III trial has compared three first-line…
Source: Nature Reviews UrologyCategories: Latest Headlines, UrologyTweet-
#ICYMI In this N&Vs Jeanny B. Aragon-Ching discusses the contrasting results of two clinical trials of pembrolizumab use in #BladderCancer https://t.co/YxahdUde8R https://t.co/UIKxPPvsHR
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Mashup Score: 1Incorporating palliative care principles to improve patient care and quality of life in urologic oncology - Nature Reviews Urology - 3 year(s) ago
Society guidelines recommend incorporating palliative care into standard oncological care. However, misconceptions regarding palliative care are common — notably, palliative care and treatments seeking to cure or prolong life are not mutually exclusive. In this article, the authors discuss the integration of palliative care into surgical urologic oncology and consider palliative care guidelines,…
Source: Nature Reviews UrologyCategories: Latest Headlines, Oncologists1Tweet-
RT @daviesbj: Make palliative care part of your conversations. Important piece by @lhugar et al Davies https://t.co/Uz5Z9ahwHt
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Mashup Score: 1Using oncolytic viruses to ignite the tumour immune microenvironment in bladder cancer - Nature Reviews Urology - 3 year(s) ago
Despite the success of immune checkpoint inhibition (ICI) in other tumour types, the majority of ICI-treated patients with bladder cancer fail to respond. This lack of efficacy might be attributable to a lack of pre-existing immune reactive cells within the tumour immune microenvironment, which limits the efficacy of ICI. In this Review, Li and colleagues discuss how oncolytic virus therapy acts…
Source: Nature Reviews UrologyCategories: Latest Headlines, UrologyTweet-
#ICYMI A Review from @UrogerliMD Jingsong Zhang @sgilbert1973 José Conejo-Garcia & @DrJamesMule discusses using oncolytic viruses to ignite the tumour immune microenvironment in #BladderCancer https://t.co/0GSunaKuYp https://t.co/S9lfQmbDRm
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Mashup Score: 3Exercise-induced myokines and their effect on prostate cancer - Nature Reviews Urology - 3 year(s) ago
Exercise improves outcomes in prostate cancer, but the mechanisms behind this are poorly understood. This Review discusses exercise-induced blood alterations, with a focus on muscle-secreted myokines, which could have both direct and indirect effects on tumour proliferation.
Source: Nature Reviews UrologyCategories: Latest Headlines, UrologyTweet-
#ICYMI In this Review Jin-Soo Kim, Daniel A. Galvão @ProfRobNewton Elin Gray & Dennis R. Taaffe discuss exercise-induced myokines and their effect on #ProstateCancer https://t.co/kCU5ry8c7q https://t.co/drTUWzG6lh
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Mashup Score: 9Cellular senescence as a possible link between prostate diseases of the ageing male - Nature Reviews Urology - 3 year(s) ago
Senescent cells and their secretome — the senescence-associated secretory phenotype (SASP) — cause a systemic pro-inflammatory state, contributing to an inflammatory microenvironment. In this article, the authors discuss the presence of senescent cells and the SASP in the ageing prostate and the evidence for a role of senescence in BPH and prostate cancer, as well as possible therapeutic…
Source: Nature Reviews UrologyCategories: Latest Headlines, UrologyTweet-
#NEWinNRU In this Review the role of cellular senescence in the pathogenesis of prostatic disease is discussed #ProstateCancer #UroBPH @GaelleFiard @VStavrinides @Emma_S_Chambers @susan_heavey @AkbarLab @EmbertonMark https://t.co/DLIHPKpaSP https://t.co/7Co7xXDMGw
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Mashup Score: 5100 years of Bacillus Calmette–Guérin immunotherapy: from cattle to COVID-19 - Nature Reviews Urology - 3 year(s) ago
Bacillus Calmette–Guérin (BCG) has been used to prevent tuberculosis for a century and is also a standard approach for the treatment of non-muscle-invasive bladder cancer. However, BCG also has a plethora of non-specific effects that occur via the induction of trained immunity and have raised the hypothesis that BCG vaccination could be used to protect against coronavirus disease 2019 (COVID-19)….
Source: Nature Reviews UrologyCategories: Latest Headlines, UrologyTweet-
#ICYMI @niyatilobo @NateBrooksMD Zlotta, Cirillo @SBoorjian @pcvblack @garysteinbergmd @JoshMeeks @tbivala1 @paolo_gontero Babjuk @djmcconkey Witjes & @UroDocAsh discuss 100 years of BCG immunotherapy https://t.co/jpkuZuVQDp https://t.co/th1VGoygEk
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Mashup Score: 0Molecular events in neuroendocrine prostate cancer development - Nature Reviews Urology - 3 year(s) ago
Neuroendocrine prostate cancer predominantly develops from adenocarcinoma following a period of androgen suppressive treatment. Outcomes in patients with this disease are poor; the understanding of the molecular mechanisms behind its development will improve future targeted therapy options.
Source: Nature Reviews UrologyCategories: Latest Headlines, UrologyTweet-
#NEWinNRU in this Review Wang et al. describe molecular events in the development of neuroendocrine #ProstateCancer https://t.co/3iw1UzNkyB https://t.co/9Uf8tSGTIj
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#NEWinNRU In this News & Views @dr_imogen and @SigridCarlsson discuss manels and manferences in urology https://t.co/HPbZIQrOC1 https://t.co/QEOeW8rIQ7