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Mashup Score: 0The interplay between virulence mechanisms is a game changer for fungal pathogenesis - 1 year(s) ago
Like Liked by Evelina Satkevic and 1 other Cryptococcus neoformans is one of four fungal species recently assigned by the World Health Organization to the most dangerous ‘critical priority group’ of fungal pathogens 1. Infections are often fatal in immunocompromised individuals, causing an estimated 112,000 deaths annually and accounting for 19% of AIDS-related mortality 2….
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Mashup Score: 5An RNA sponge modulates quorum sensing dynamics - 1 year(s) ago
Like Liked by Sridhar Ranganathan and 4 others Bacteria can sense their population density through a process called quorum sensing (QS). QS relies on the secretion, detection and response to extracellular signaling molecules termed autoinducers (AI). Thereby, QS controls various complex behaviors in Vibrio cholerae, including virulence factor expression and biofilm formation (1,2). At…
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An RNA sponge modulates quorum sensing dynamics @papenfortlab @AnneLippegaus #microbiology #biofilms #QuorumSensing https://t.co/aJ9bklHklt https://t.co/E7Z0nXe7Q8
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Mashup Score: 15Guardians of the progeny: How ectosymbionts protect molting life stages of a beetle against fungal infection - 1 year(s) ago
Molting enables insects to grow and develop, but also temporally removes a very important layer of protection – the cuticle. Immature stages of Lagria beetles are defended during this vulnerable phase by cuticle-associated symbionts which are housed in three dorsal pockets and produce antibiotics.
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Insects moult their protective cuticle during growth, but immature Lagria beetles have antibiotic-filled symbionts to defend them during this vulnerable stage, Rebekka Janke and Laura Flórez write in a Nature Portfolio Microbiology Community post. https://t.co/Pib6laXNTD
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Mashup Score: 11
Like Liked by Evelina Satkevic and 1 other Upon infection, a host will try to reduce pathogen numbers by producing an immune response towards them. However, depending on various factors, such as host-pathogen genotypes (e.g., coevolutionary history) or host energetic reserves, it might not be able to clear them (Figure 1). In short, there are three different infection outcomes:…
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When organisms are bacterially infected, hosts can clear the infection, succumb to the pathogen or survive with a persistent infection. In the Nature Portfolio Microbiology Community, @luismmsilva_ discusses infection tolerance versus pathogen resistance. https://t.co/Um0K3vhT5I
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Mashup Score: 0Aerosolization of fusion inhibitory peptide protects monkeys from measles virus infection - 2 year(s) ago
Like Liked by Evelina Satkevic and 2 others Measles virus (MeV) leads to one of the most contagious airborne viral infection worldwide, causing 3 to 4 million cases annually with 207.500 deaths in 20191. Infection is followed by an immunosuppressive state, responsible of numerus complications2,3. Despite an effective live vaccine strategy, measles remains one of the leading…
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Aerosolization of fusion inhibitory peptide protects monkeys from measles virus infection @brankahorvat88 @CIRI_Lyon #Measles #VaccinesWork https://t.co/kYn3XVu3Gn https://t.co/NL99WM2ySH
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Mashup Score: 0
To what extent do vaccine and infection determine the antibody responses of an individual in terms of breadth and magnitude to a wide range of SARS-CoV-2 and relevant viruses? Here is your answer.
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Spread it out: mRNA advantage for antibody coverage against SARS-type viruses To what extent do vaccine and infection determine antibody responses to #SARSCoV2 and related viruses? @svalko03 @linfa_wang @cheeWahTan2 @Janice22461665 @MalikP46697504 https://t.co/B1flZDufwg
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Mashup Score: 4
A stunning 2.5 to 4 billion years ago, in a period known as the Archaean Eon, the first forms of life appeared on Earth. These primordial organisms were likely simple cells enclosed in a cell membrane, in contrast to the diverse and complex microbes we know today. It is thought that horizontal gene transfer (HGT), or the exchange of genetic material between cells, took place on a large scale1….
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On the origin of life: Endocytosis-like DNA uptake by cell wall-deficient bacteria "How could early forms of life take up DNA or other particles, when specialized uptake machineries had not yet evolved?" @KapteijnRenee @ClaessenLAB @GillesvanWezel https://t.co/2SXBgAqmZl https://t.co/8sQyoO0iM8
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Mashup Score: 20A compendium of 32,277 metagenome-assembled genomes and over 80 million genes from the early-life human gut microbiome - 2 year(s) ago
Given the specificity of early-life human gut microbiome regarding the microbial composition and functions, building a set of high-quality reference genomes from early life is desirable for a good microbial characterization, and discovering interactions between early-life gut microbiome and health.
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The early-life gut microbiome has important links to human health as we grow up. Shaopu Wang discusses in the Nature Portfolio Microbiology Community the creation of the Early-Life Gut Genomes and Proteins catalogues, consisting of over 80 million genes. https://t.co/0YfKH5yNa3 https://t.co/CketKew9L0
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Mashup Score: 4Immunocompromised in the Omicron Era - 2 year(s) ago
How does prior vaccination and infection impact immunity to the highly transmissible Omicron variant in immunocompromised transplant recipients?
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Immunocompromised in the Omicron Era How does prior #vaccination & infection impact immunity to the Omicron variant in immunocompromised transplant recipients? @FerreiraVHF @JTsolera @dktransplant @HumarAtul @uhn_research @UHNtransplant #COVID https://t.co/C9D6Cv8gvk https://t.co/I1axVUCr78
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Mashup Score: 4In the air tonight: COVID testing spaces, not faces. - 2 year(s) ago
Developing alternative environmental testing strategies to improve viral surveillance.
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In a Nature Portfolio Microbiology Community post, @MitchellRamuta writes about research into COVID-19 air surveillance strategies that could be used with wastewater testing to provide hyperlocal data with high spatial resolution within a community. https://t.co/0d7gwM2T6a
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The interplay between virulence mechanisms is a game changer for fungal pathogenesis #Cryptococcus The story #BehindThePaper by Rosanna Baker & @ACasadevall1 : "This project, as many discoveries in science, began with a serendipitous observation..." https://t.co/4dAH1yfaxj https://t.co/73A9dXNtP6