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Mashup Score: 0
Radiotherapy-induced xerostomia (RIX) significantly affects quality of life in head and neck cancer (HNC) survivors. Neuro-electrostimulation of the salivary glands may safely increase natural salivation and reduce dry mouth symptoms.
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 5Phase 1 Dose Escalation Study of SBRT Using 3 Fractions for Locally Advanced Pancreatic Cancer - 1 year(s) ago
The optimal dose and fractionation of stereotactic body radiation therapy (SBRT) for locally advanced pancreatic cancer (LAPC) have not been defined. Single-fraction SBRT was associated with more gastrointestinal toxicity, so 5-fraction regimens have become more commonly employed. We aimed to determine the safety and maximally tolerated dose of 3-fraction SBRT for LAPC.
Categories: Hem/Oncs, Latest HeadlinesTweet-
In our newest paper, we explored a 3-fraction regimen of stereotactic body radiotherapy (SBRT) for locally advanced pancreatic cancer. We found no dose-limiting toxicities & maintenance of patients' quality of life. Learn more: https://t.co/YKgnQTlLTb https://t.co/3EmXX7IAJW
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Mashup Score: 4Phase 1 Dose Escalation Study of SBRT Using 3 Fractions for Locally Advanced Pancreatic Cancer - 1 year(s) ago
The optimal dose and fractionation of stereotactic body radiation therapy (SBRT) for locally advanced pancreatic cancer (LAPC) have not been defined. Single-fraction SBRT was associated with more gastrointestinal toxicity, so 5-fraction regimens have become more commonly employed. We aimed to determine the safety and maximally tolerated dose of 3-fraction SBRT for LAPC.
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
New in the #RedJournal: For locally advanced pancreatic cancer, dose escalation to the target dose of 33Gy in 3 fractions resulted in no DLTs, no detriment to the QoL and disease outcomes comparable to conventional RT. https://t.co/whjq0ae7Oa https://t.co/ObVTRLE43a
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Mashup Score: 3
: To determine the safety and tolerability of combining stereotactic ablative radiotherapy (SABR) and durvalumab with respect to rates of Grade ≥3 non-hematological toxicity in medically inoperable patients with early-stage non-small cell lung cancer (NSCLC).
Categories: Hem/Oncs, Latest HeadlinesTweet-
Here is the local control rate for 18 patients with stage I NSCLC enrolled from 2017-2020 in a phase II clinical trial evaluating the safety and efficacy of SBRT + Durvalumab. @trudywu2 #radonc https://t.co/s9yhmLdGxu https://t.co/l1gJHyS2rH
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Mashup Score: 1The Artistry of Radiation Oncology: Raiders of the Lost Art - 1 year(s) ago
In this era when technology dominates the field of radiation oncology, one would logically assume that improved technology can translate into improved treatment outcome. The artistry aspect of radiation contouring and planning—which is as important, if not more, than advanced technology—is frequently forgotten. Recent research and development in radiation oncology have focused exclusively on how…
Categories: Hem/Oncs, Latest HeadlinesTweet-
"In this era when technology dominates the field of radiation oncology...the artistry is frequently forgotten." Shiny tools/fancy tech do not compensate for sloppy target delineation, or guarantee better outcomes. Enjoyed this piece from Annie Chan. https://t.co/rXbdgquUK9
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Mashup Score: 3
Pulmonary complications, especially idiopathic pneumonitis syndrome (IPS), are potentially life altering or fatal sequelae of hematopoietic cell transplantation (HCT). Total body irradiation (TBI) as part of the conditioning regimen has been implicated in IPS. A comprehensive PENTEC (Pediatric Normal Tissues in the Clinic) review was performed to increase our understanding of the role of TBI in…
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
New #RedJournal publication from the PENTEC group: Correlation of TBI Dose and Idiopathic Pneumonitis. @DrEricEhler @dusen001 @umnradonc https://t.co/SDF66NaRbt https://t.co/apd89HkeEI
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Mashup Score: 0
To compare transarterial chemoembolization delivered with drug eluting beads (TACE-DEB) with stereotactioc body radiation therapy (SBRT) in patients with hepatocellular carcinoma (HCC) in a multicenter randomized trial.
Categories: Latest Headlines, Oncologists2Tweet-
TACE vs. SBRT for HCC: randomized phase II TRENDY trial - stoped early due to poor a accrual - all endpoints significantly or numerically better after SBRT 👉 time to progression 19 vs 12 mo 👉 median OS 44 vs 37 mo 👉2a local control 100% vs 44% CONGRATS https://t.co/XQt9uNqiIs
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Mashup Score: 8A Story of Hypofractionation and the Table on the Wall - 1 year(s) ago
I was recently informed that I won a contest that I did not actually enter. A Twitter poll was organized through @Radiation Nation inspired by Sue Yom, the new editor of the journal, asking, “What do people consider the gold standard for treatment planning for hypofractionated RT?” Response options were “HyTEC; AAPM TG-101; Timmerman Sheet; and NRG/RTOG protocols.” With just over 100 total votes…
Categories: Hem/Oncs, Latest HeadlinesTweet-
Since we're on the topic of radiation dosing, this piece in @IJROBP by Timmerman on SAbR & constraints is a MUST read. Re: Timmerman constraints: "In all honesty, except for spinal cord, all other limits for the original table were my educated guesses." https://t.co/fJbJOrPpL4
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Mashup Score: 1Predicted Inferior Outcomes for Lung SBRT With Treatment Planning Systems That Fail Independent Phantom-Based Audits - 1 year(s) ago
More than 15% of radiation therapy clinics fail external audits with anthropomorphic phantoms conducted by Imaging and Radiation Oncology Core-Houston (IROC-H) while passing other industry-standard quality assurance (QA) tests. We seek to evaluate the predicted effect of such failed plans on outcomes for patients treated with stereotactic body radiation therapy (SBRT) for lung tumors.
Categories: Latest Headlines, Oncologists2Tweet-
Here's a reason why all lung SBRT devices should be credentialed by the NCI-funded IROC program. Thank you @QuadShotNews, for highlighting this important article. #radonc https://t.co/7QIBRBrXb0 https://t.co/xTuhGIWqXY
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Mashup Score: 0The Updated WHO Classification Better Predicts Survival in Patients with Endocervical Adenocarcinoma (KROG 20-07) - 1 year(s) ago
The 2020 World Health Organization (WHO) classification divided endocervical adenocarcinoma (ADC) into human papillomavirus (HPV)-associated (HPVA) and HPV-independent (HPVI) ADCs. This multi-institutional study aimed to investigate the clinical features and prognosis of patients with endocervical ADC based on the updated WHO classification.
Categories: Healthcare Professionals, Latest HeadlinesTweet-
The Updated @WHO Classification Better Predicts Survival in Patients with Endocervical Adenocarcinoma (KROG 20-07) #gyncsm #radonc #gynpath in @IJROBP https://t.co/h1eKtPcZUL
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New in the #RedJournal from @ValeMercadante: salivary electrostimulation in the treatment of radiotherapy-induced xerostomia (LEONIDAS-2): a multicentre, randomised, double-masked sham-controlled phase 3 trial. https://t.co/JQEwQjBlbL https://t.co/dZ53tCyHZL