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Mashup Score: 2Myeloid neoplasms post PARP inhibitors for ovarian cancer - 1 year(s) ago
The incidence of myeloid neoplasms following treatment with poly (ADP-ribose) polymerase inhibitors (PARPi) in patients with ovarian cancer has been gradually increasing over the last few years. The cumulative exposure to PARPi and the improved overall survival of patients with ovarian cancer may represent key underlying explanations behind such trend. Fortunately, the earlier introduction of…
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 3
Currently licensed human papillomavirus (HPV) vaccines are very effective against cervical cancer and pre-cancer and probably also effective against five additional HPV-related cancers with no available screening strategies.[1][1] Antibodies triggered by the vaccine are different from antibodies
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 2
Currently licensed human papillomavirus (HPV) vaccines are very effective against cervical cancer and pre-cancer and probably also effective against five additional HPV-related cancers with no available screening strategies.[1][1] Antibodies triggered by the vaccine are different from antibodies
Categories: Latest Headlines, Oncologists2Tweet
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Mashup Score: 1ECO-LEAK technique: early detection of colorectal anastomotic leakage by transvaginal ultrasound - 1 year(s) ago
Modified posterior pelvic exenteration or colorectal resection followed by an end-to-end colorectal anastomosis are common procedures during cytoreduction.[1][1] Anastomotic leak represents a clinical challenge that delays patients’ recovery and oncologic treatment, with a direct negative impact
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Mashup Score: 2Can fluorescence-guided surgery improve optimal surgical treatment for ovarian cancer? A systematic scoping review of clinical studies - 1 year(s) ago
Background The predicament of achieving optimal surgical intervention faced by surgeons in treating ovarian cancer has driven research into improving intra-operative detection of cancer using fluorescent materials. Objective To provide a literature overview on the clinical use of intra-operative fluorescence-guided surgery for ovarian cancer, either for cytoreductive surgery or sentinel lymph…
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Mashup Score: 9
The clinical development of antibody drug conjugates (ADCs) in ovarian cancer began in 2008 with farletuzumab, a humanized monoclonal antibody, and vintafolide, an antigen drug conjugate, both targeting alpha folate receptor. Over the years, this novel class of drugs expanded to agents with a more sophisticated design and structure, targeting tissue factor (TF) in cervical cancer or human…
Categories: Latest Headlines, Oncologists2Tweet
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Mashup Score: 14Advances in immunotherapy in cervical cancer - 1 year(s) ago
Cervical cancer represents a major public health problem, being the fourth most common cancer in incidence and mortality in women worldwide. Patients with recurrent, persistent, or metastatic disease unsuitable for curative therapeutic approaches have a dismal prognosis. Until recently, these patients were only candidates for cisplatin-based chemotherapy plus bevacizumab. However, the…
Categories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 4Advances in immunotherapy in cervical cancer - 1 year(s) ago
Cervical cancer represents a major public health problem, being the fourth most common cancer in incidence and mortality in women worldwide. Patients with recurrent, persistent, or metastatic disease unsuitable for curative therapeutic approaches have a dismal prognosis. Until recently, these patients were only candidates for cisplatin-based chemotherapy plus bevacizumab. However, the…
Categories: Latest Headlines, Oncologists2Tweet
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Mashup Score: 3Advances in immunotherapy in cervical cancer - 1 year(s) ago
Cervical cancer represents a major public health problem, being the fourth most common cancer in incidence and mortality in women worldwide. Patients with recurrent, persistent, or metastatic disease unsuitable for curative therapeutic approaches have a dismal prognosis. Until recently, these patients were only candidates for cisplatin-based chemotherapy plus bevacizumab. However, the…
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 4
Drug development is paramount to improve outcomes in patients with gynecologic cancers. A randomized clinical trial should measure whether a clinically relevant improvement is detected with the new intervention compared with the standard of care, using reproductible and appropriate endpoints. Clinically meaningful improvements in overall survival and/or quality of life (QoL) are the gold…
Categories: Latest Headlines, Oncologists2Tweet
RT @IJGConline: #Review Myeloid neoplasms post PARP inhibitors for #OvarianCancer @gcarusomd 🆓 https://t.co/E5QxU4qYvD @pedroramirezMD @H…