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Mashup Score: 7Inherited Bleeding Disorders - 3 year(s) ago
HEMATOLOGY/ONCOLOGY CLINICS OF NORTH AMERICA
Source: Hematology/Oncology ClinicsCategories: Hematologists1, Latest HeadlinesTweet
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Mashup Score: 0Immune Therapy for Chronic Lymphocytic Leukemia - 3 year(s) ago
Despite significant improvement in clinical outcomes of chronic lymphocytic leukemia (CLL), patients who experience failure of Bruton tyrosine kinase inhibitors or venetoclax benefit from immune therapy approaches. Allogeneic transplant is a potentially curative treatment of CLL but is associated with risk of morbidity and mortality. Although still experimental, chimeric antigen receptor T-cell…
Source: Hematology/Oncology ClinicsCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 5
Myeloproliferative neoplasms are characterized by chronic inflammation. The discovery of constitutively active JAK-STAT signaling associated with driver mutations has led to clinical and translational breakthroughs. Insights into the other pathways and novel factors of potential importance are being actively investigated. Various classes of agents with immunomodulating or immunosuppressive…
Source: Hematology/Oncology ClinicsCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 1Quality of Life in Myeloproliferative Neoplasms - 3 year(s) ago
Myeloproliferative neoplasms include essential thrombocythemia, polycythemia vera, and myelofibrosis. They are characterized by abnormal myeloid proliferation. Patients suffer from debilitating constitutional symptoms and splenomegaly. There have been advances in understanding the impact on quality of life in myeloproliferative neoplasms. Owing to the chronicity of these diseases, symptoms are…
Source: Hematology/Oncology ClinicsCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 1
The management of bladder cancer has witnessed several multidisciplinary advances in the past few years (Fig. 1). This issue of the Hematology/Oncology Clinics of North America takes the reader on an exciting journey highlighting the recent advances. Metastatic urothelial carcinoma (mUC) is generally incurable. Cisplatin-based combination chemotherapy yields a median survival of 14 to 15 months…
Source: Hematology/Oncology ClinicsCategories: Latest Headlines, UrologyTweet
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Mashup Score: 9
The management of bladder cancer has witnessed several multidisciplinary advances in the past few years (Fig. 1). This issue of the Hematology/Oncology Clinics of North America takes the reader on an exciting journey highlighting the recent advances. Metastatic urothelial carcinoma (mUC) is generally incurable. Cisplatin-based combination chemotherapy yields a median survival of 14 to 15 months…
Source: Hematology/Oncology ClinicsCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 3Unmet Need in Essential Thrombocythemia and Polycythemia Vera - 4 year(s) ago
Consensus guidelines have helped to standardize the care of patients with essential thrombocythemia and polycythemia vera, focusing on reducing the risk of thrombosis, mitigating symptoms, and avoiding therapies that may accelerate disease progression. However, many unmet needs still exist ranging from the roll of antiplatelet therapy in ET to medications that reduce disease progression….
Source: Hematology/Oncology ClinicsCategories: Latest Headlines, PediatricsTweet
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Mashup Score: 0Treatment of Acquired Sideroblastic Anemias - 5 year(s) ago
Sideroblastic anemias are a heterogeneous group of disorders unified by the presence of abnormal erythroid precursors with perinuclear mitochondrial iron deposition in the bone marrow. Based on etiology, they are classified into clonal and nonclonal. Clonal sideroblastic anemias refer to myeloid neoplasms with ring sideroblasts (RS) and frequently have somatic perturbations in the SF3B1 gene….
Source: Hematology/Oncology ClinicsCategories: Hem/OncsTweet
A comprehensive resource of topics on Inherited Bleeding Disorders edited by @NTConnell for Hematology/Oncology Clinics. Thank you for the opportunity to contribute to this! https://t.co/jKil1opQ3t