Ebstein anomaly (EA), a form of congenital heart disease (CHD) that occurs in 1 to 20 000 live births, consists of a distinctive malformation of the right ventricle and tricuspid valve with adherence of septal and posterior leaflets to the underlying myocardium due to failure of embryological delamination. The consequent right atrial enlargement combined with the high prevalence of accessory…

Objective Beta-blockers (BB) are an established treatment following myocardial infarction (MI). However, there is uncertainty as to whether BB beyond the first year of MI have a role in patients without heart failure or left ventricular systolic dysfunction (LVSD). Methods A nationwide cohort study was conducted including 43 618 patients with MI between 2005 and 2016 in the Swedish register for…

Background The prevalence of anaemia and iron deficiency and their prognostic association with cardiovascular disease have rarely been explored at population level. Methods National Health Service records of the Greater Glasgow region for patients aged ≥50 years with a broad range of cardiovascular diagnoses were obtained. During 2013/14, prevalent disease was identified and results of…

Objective There is uncertainty about surgical procedures for adult patients aged 18–60 years undergoing aortic valve replacement (AVR). Options include conventional AVR (mechanical, mAVR; tissue, tAVR), the pulmonary autograft (Ross) and aortic valve neocuspidisation (Ozaki). Transcatheter treatment may be an option for selected patients. We used formal consensus methodology to make…

Coronary artery disease is a serious condition increasingly affecting young adults.1 2 Despite recent improvements in primary prevention of cardiovascular (CV) disease in older patients, identifying younger adults at risk of events who would benefit from an intensive preventive strategy remains challenging,3 even if they carry traditional, actionable cardiovascular risk factors. The Appraisal of…

Objective Evidence on long-term costs of atrial fibrillation (AF) and associated factors is scarce. As part of the Swiss-AF prospective cohort study, we aimed to characterise AF costs and their development over time, and to assess specific patient clusters and their cost trajectories. Methods Swiss-AF enrolled 2415 patients with variable duration of AF between 2014 and 2017. Patient clusters…

Objective To investigate the association of accelerometer-measured lifestyle physical activity with rapid-rate non-sustained ventricular tachycardias (RR-NSVTs) in patients with arrhythmogenic cardiomyopathy (AC). Methods This multicentre, observational study enrolled 72 patients with AC, including right, left and biventricular forms of the disease, with underlying desmosomal and non-desmosomal…