Heart failure (HF) is a growing global public health problem affecting at least 26 million people worldwide. The evidence-based landscape for HF treatment has changed at a rapid rate over the last 30 years. International guidelines for the management of HF now recommend the use of four pillars in all patients with reduced ejection fraction: angiotensin receptor neprilysin inhibitors or ACE…

The diagnostic yield of endomyocardial biopsy in cardiac sarcoidosis (CS) is quite low because of the patchy involvement, and for the diagnosis of CS, existing guidelines required histological confirmation. Therefore, especially for isolated CS, diagnosis consistent with the guidelines cannot be made in a large number of patients. With recent developments in imaging modalities such as cardiac…

Heart failure (HF) is a global public health concern that affects millions of people worldwide. While there have been significant therapeutic advancements in HF over the last few decades, there remain major disparities in risk factors, treatment patterns and outcomes across race, ethnicity, socioeconomic status, country and region. Recent research has provided insight into many of these…

Objectives To generate contemporary age-specific mortality rates for Indigenous and non-Indigenous Australians aged <65 years who died from rheumatic heart disease (RHD) between 2013 and 2017, and to ascertain the underlying causes of death (COD) of a prevalent RHD cohort aged <65 years who died during the same period. Methods For this retrospective, cross-sectional epidemiological study,...

### Learning objectives Out-of-hospital sudden cardiac arrest (OHCA) is a major issue of public health with more than 350 000 deaths per year in the USA and 275 000 in Europe, accounting for almost half of cardiovascular mortality.1 Survival rate remains low, with survival to hospital discharge rarely exceeding 10%, except in some cities where huge efforts were invested in this field.2 3 The…

Read about and listen to Heart journal’s most recent podcast episodes. Subscribe on Spotify, Apple, Stitcher and Google Podcasts.