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    Bhattacharyya et al (J Clin Invest 2023;133:e153635, PMID 36454649) globally profiled the mouse cardiac conduction system (CCS) cis-regulatory landscape by genetically tagged CCS component-specific nuclei for comprehensive assay for transposase-accessible chromatin-sequencing (ATAC-Seq) analysis. A global CCS-enriched cis-regulatory element (CRE) database, referred to as CCS-ATAC, was established…

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    • EP News: Basic and Translational https://t.co/9nvz1Ibmxa

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    EP News: Case Reports - 1 year(s) ago

    Leadless pacemaker technologies have matured to the point that patients have reached a time in which device replacements are required for various reasons. In the setting of a retained device at the time of device replacement, there is the potential for device-to-device interactions. Frazer et al (https://doi.org/10.1016/j.hrcr.2023.03.001) share the case of a 62-year-old man with end-stage renal…

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    • EP News: Case Reports, by @TJaredBunch https://t.co/oak2OqUdk4

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    The last year has shown that the Heart Rhythm Society (HRS) cannot be too prepared for a crisis and that members need a powerful advocate in their corner as they navigate their busy, demanding careers. HRS has embraced being a voice for the field of electrophysiology (EP) as 1 of 3 priorities of the new 2023–2026 strategic plan that the Board of Trustees has recently drafted and endorsed. As you…

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    • President's Page: HRS Leadership perspective on the Medicare reimbursement follow-up survey, by @AndrewKrahnMD and Jodie L. Hurwitz, MD, FHRS https://t.co/b92gKseTOc

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    Cardioinhibitory carotid sinus syndrome (CSS) is a neurally mediated (reflex) syncope, secondary to excessive vagal response to carotid sinus pressure. A growing body of studies have shown that catheter ablation of ganglionated plexi (GPs) or cardioneuroablation (CNA) is effective in treating patients with vasovagal syncope.1 To date, no studies systematically evaluated CNA in patients with CSS.

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    • Cardioneuroablation for carotid sinus syndrome: a case series @DrBerruezo https://t.co/xUB022YL8e