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Mashup Score: 0
Risk stratification is useful in predicting outcomes and guiding treatment of patients with PAH, aiming to reach a low mortality risk; in addition to validated risk tools, PVR-associated markers are increasingly relevant in guiding treatment decisions. https://bit.ly/4cHFY6H
Source: erj.ersjournals.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 2Treatment algorithm for pulmonary arterial hypertension - 3 month(s) ago
In this document from the 7th World Symposium on Pulmonary Hypertension, an updated treatment algorithm is outlined. Medications targeting four pathways are now available, and initial combination therapy with early and frequent reassessment is recommended. https://bit.ly/46ctth4
Source: erj.ersjournals.comCategories: General Medicine News, Critical CareTweet-
Treatment algorithm for pulmonary arterial hypertension https://t.co/7qjeSlz7gR https://t.co/NBv4BmURjk
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Mashup Score: 25How many functioning ciliated airway epithelial cells are necessary for effective mucociliary clearance? - 4 month(s) ago
In the current issue of the European Respiratory Journal, Loges and co-workers use an elegant approach to demonstrate that 30% of normally functioning ciliated epithelial cells may be sufficient to maintain mucociliary clearance in vitro and in vivo https://bit.ly/3YHJtpv
Source: erj.ersjournals.comCategories: General Medicine News, PulmonologyTweet-
In the current issue of the European Respiratory Journal, Loges and co-workers use an elegant approach to demonstrate that 30% of normally functioning ciliated epithelial cells may be sufficient to maintain mucociliary clearance in vitro and in vivo https://t.co/Mmhl3HJxyj https://t.co/SNIcr42TI2
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Mashup Score: 20A range of 30–62% of functioning multiciliated airway cells is sufficient to maintain ciliary airway clearance - 4 month(s) ago
Restoring cilia function in 30–62% of defective respiratory cells is sufficient to improve ciliary clearance in PCD individuals https://bit.ly/45PQQg9
Source: erj.ersjournals.comCategories: General Medicine News, PulmonologyTweet-
European Respiratory Journal: Restoring cilia function in 30–62% of defective respiratory cells is sufficient to improve ciliary clearance in PCD individuals https://t.co/F2VrYEfsWF https://t.co/Ub3UlAuDDZ
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Mashup Score: 53Exacerbation history and blood eosinophil count prior to diagnosis of COPD and risk of subsequent exacerbations - 4 month(s) ago
In newly diagnosed patients, a single exacerbation prior to diagnosis of COPD is associated with a significant risk of exacerbations over the next 12 months, and more frequent or severe exacerbations prior to diagnosis are associated with a higher risk https://bit.ly/4fhTSOm
Source: erj.ersjournals.comCategories: General Medicine News, PulmonologyTweet-
In newly diagnosed patients, a single exacerbation prior to diagnosis of COPD is associated with a significant risk of exacerbations over the next 12 months, and more frequent or severe exacerbations prior to diagnosis are associated with a higher risk https://t.co/1siEYoUAPR https://t.co/96PuLu6Rrf
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Mashup Score: 11Local receptor-interacting protein kinase 2 inhibition mitigates house dust mite-induced asthma - 4 month(s) ago
Intranasal therapeutic inhibition of RIPK2 attenuates crucial features of experimental asthma in humanised NOD1 mice, and acts on epithelial cells from asthma patients, by downregulating pro-allergenic chemokines and TSLP https://bit.ly/3WnfIZk
Source: erj.ersjournals.comCategories: General Medicine News, PulmonologyTweet-
European Respiratory Journal: Intranasal therapeutic inhibition of RIPK2 attenuates crucial features of experimental asthma in humanised NOD1 mice, and acts on epithelial cells from asthma patients, by downregulating pro-allergenic chemokines and TSLP https://t.co/KBt6sn69iG https://t.co/77KtUVSviu
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Mashup Score: 18COPD-iNET: a call to the lung community for action to combat the global epidemic of COPD - 4 month(s) ago
COPD is a devastating disease that requires a renewed community effort to ignite innovative research directions and therapeutic avenues, which is being addressed by COPD-iNET to foster new collaborations and ideas to transform our understanding of COPD https://bit.ly/3Apscah
Source: erj.ersjournals.comCategories: General Medicine News, PulmonologyTweet-
COPD is a devastating disease that requires a renewed community effort to ignite innovative research directions and therapeutic avenues, which is being addressed by COPD-iNET to foster new collaborations and ideas to transform our understanding of COPD https://t.co/EQxqN7QFTD https://t.co/gK0k3i6dbc
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Mashup Score: 31Association of airway inflammation and smoking status with IL-33 level in sputum of patients with asthma or COPD - 4 month(s) ago
In patients with COPD, targeting IL-33 might be auspicious in former smokers. However, disease severity should also be considered. In patients with severe asthma, targeting IL-33 might be a potential treatment option, irrespective of T2-status. https://bit.ly/3SFspww
Source: erj.ersjournals.comCategories: General Medicine News, PulmonologyTweet-
ERJ: In patients with COPD, targeting IL-33 might be auspicious in former smokers. However, disease severity should also be considered. In patients with severe asthma, targeting IL-33 might be a potential treatment option, irrespective of T2-status. https://t.co/jbF9faDc30 https://t.co/dOKtxeliGF
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Mashup Score: 14An interdisciplinary consensus approach to pulmonary hypertension in developmental lung disease - 4 month(s) ago
Interdisciplinary consensus is presented for approaches to improve clinical recognition, more efficient diagnosis and tailored treatment for infants with pulmonary hypertension due to developmental lung disease https://bit.ly/4c0hPH8
Source: erj.ersjournals.comCategories: General Medicine News, PulmonologyTweet-
ERJ: Interdisciplinary consensus is presented for approaches to improve clinical recognition, more efficient diagnosis and tailored treatment for infants with pulmonary hypertension due to developmental lung disease https://t.co/y5l2RRPEr1 https://t.co/C34YgoPzLN
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Mashup Score: 3
Pulmonary ischaemia–reperfusion injury accounts for significant morbidity after lung transplant but has no known medical therapies. This study identified a critical role for the natural killer cell co-receptor CD94 in mouse and human lung transplant. https://bit.ly/3WdSghb
Source: erj.ersjournals.comCategories: General Medicine News, PulmonologyTweet-
ERJ: Pulmonary ischaemia–reperfusion injury accounts for significant morbidity after lung transplant but has no known medical therapies. This study identified a critical role for the natural killer cell co-receptor CD94 in mouse and human lung transplant. https://t.co/KAt2Iv18J2 https://t.co/bG8GtZNNnY
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Risk stratification and treatment goals in pulmonary arterial hypertension. The Seventh World Symposium on Pulmonary Hypertension #PAH https://t.co/PiD1fz0C6A https://t.co/Tj5Ijm8vCC