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Mashup Score: 0Predicting survival and neurological outcome in out-of-hospital cardiac arrest using machine learning: the SCARS model - 1 year(s) ago
Thirty-day survival and neurological outcome in OHCA can rapidly and reliably be estimated during ongoing cardiopulmonary resuscitation in the emergency room using a machine learning model incorporating widely available variables.
Source: EBioMedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 0Predicting survival and neurological outcome in out-of-hospital cardiac arrest using machine learning: the SCARS model - 1 year(s) ago
Thirty-day survival and neurological outcome in OHCA can rapidly and reliably be estimated during ongoing cardiopulmonary resuscitation in the emergency room using a machine learning model incorporating widely available variables.
Source: EBioMedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
3rd highlight of March issue @FHessulf & coll proposed a prediction model that estimates survival and neurological outcome in out-of-hospital cardiac arrest patients Read https://t.co/mSxMo7j3fL and thread ⤵️ https://t.co/8dT37xlE3S https://t.co/ObsVw6rjVp
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Mashup Score: 1
These findings provide evidence that local B cells at least in late-stage MS preferentially mature into ASCs, which are largely responsible for intrathecal and local Ig production. This is especially seen in active MS white matter lesions and likely depends on the interaction with CD4+ memory T cells.
Source: EBioMedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
2nd highlight from March issue L Bogers et al from @ErasmusMC explored B-cell maturation in the central nervous system (CNS) of #MS patients and determined their association with immunoglobulin production, T-cell presence, and lesion formation. Read https://t.co/YAsawZfF5i https://t.co/l4IS9FkjV1
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Mashup Score: 1
These findings provide evidence that local B cells at least in late-stage MS preferentially mature into ASCs, which are largely responsible for intrathecal and local Ig production. This is especially seen in active MS white matter lesions and likely depends on the interaction with CD4+ memory T cells.
Source: EBioMedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
2nd highlight from March issue L Bogers et al from @ErasmusMC explored B-cell maturation in the central nervous system (CNS) of #MS patients and determined their association with immunoglobulin production, T-cell presence, and lesion formation. Read https://t.co/YAsawZgcUQ https://t.co/rCtPx2zo9V
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Mashup Score: 0A unified classification approach rating clinical utility of protein biomarkers across neurologic diseases - 1 year(s) ago
A major evolution from purely clinical diagnoses to biomarker supported clinical diagnosing has been occurring over the past years in neurology. High-throughput methods, such as next-generation sequencing and mass spectrometry-based proteomics along with improved neuroimaging methods, are accelerating this development. This calls for a consensus framework that is broadly applicable and provides a…
Source: EBioMedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
1st highlight from Mar issue @BernhardtAM & coll propose a unified classification approach rating clinical utility of protein biomarkers across neurologic diseases Read https://t.co/KOK6XduKDp https://t.co/wZjIEAJBix
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Mashup Score: 0A unified classification approach rating clinical utility of protein biomarkers across neurologic diseases - 1 year(s) ago
A major evolution from purely clinical diagnoses to biomarker supported clinical diagnosing has been occurring over the past years in neurology. High-throughput methods, such as next-generation sequencing and mass spectrometry-based proteomics along with improved neuroimaging methods, are accelerating this development. This calls for a consensus framework that is broadly applicable and provides a…
Source: EBioMedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
1st highlight from Mar issue @BernhardtAM & coll propose a unified classification approach rating clinical utility of protein biomarkers across neurologic diseases Read https://t.co/KOK6XducNR https://t.co/oSBnuXUP07
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Mashup Score: 0Association between proteomic biomarkers and myocardial fibrosis measured by MRI: the multi-ethnic study of atherosclerosis - 1 year(s) ago
Cardiac magnetic resonance imaging (CMR) determines the extent of interstitial fibrosis, measured by increased extracellular volume (ECV), and replacement fibrosis with late gadolinium myocardial enhancement (LGE). Despite advances in detection, the pathophysiology of subclinical myocardial fibrosis is incompletely understood. Targeted proteomic discovery technologies enable quantification of low…
Source: EBioMedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
NEW Association btw 2 types of myocardial fibrosis by #whyCMR and 92 #CVD #proteomic biomarkers in a subgroup of MESA pts. 17 proteins associated with interstitial MF, none with replacement MF ➡️different mech pathways #CardioTwitter, @BakhshiHooman Read https://t.co/xD9okbRu2y
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Mashup Score: 0Attention is not all you need: the complicated case of ethically using large language models in healthcare and medicine - 1 year(s) ago
Large Language Models (LLMs) are a key component of generative artificial intelligence (AI) applications for creating new content including text, imagery, audio, code, and videos in response to textual instructions. Without human oversight, guidance and responsible design and operation, such generative AI applications will remain a party trick with substantial potential for creating and spreading…
Source: EBioMedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Important thoughts on the development and deployment of generative AI applications in health sectors shared by Stefan Harrer in this piece. Read https://t.co/YoNGgi4IiF https://t.co/3xqNoPsHbI
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Mashup Score: 0A high-throughput sequencing approach identifies immunotherapeutic targets for bacterial meningitis in neonates - 1 year(s) ago
Altogether, these results indicate the utility of a high-throughput DNA sequencing method to identify potential immunotherapy targets for a pathogen, including in this study a potential broad-spectrum target for prevention of neonatal bacterial infections.
Source: EBioMedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
2nd highlight of Feb Dr Pons & coll used Transposon Sequencing to evaluate Ecoli K1 genetic fitness in mice neonatal meningitis suggest utility of a high-throughput DNA sequencing method to identify potential immunotherapy targets for a pathogen Read https://t.co/Uyr7jBnJdg https://t.co/C3UyOWZjN1
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Mashup Score: 0Causal effects of maternal circulating amino acids on offspring birthweight: a Mendelian randomisation study - 1 year(s) ago
Our findings strengthen evidence for key roles of maternal circulating amino acids during pregnancy in healthy fetal growth.
Source: EBioMedicineCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
1st highlight of Feb @jianzhao_jz & coll explored the effect of maternal circulating amino acids on fetal growth, proxied by birthweight, using two-sample Mendelian randomization Read https://t.co/lgJ05zeZTy https://t.co/kZD8bY8wsK
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3rd highlight of March issue @FHessulf & coll proposed a prediction model that estimates survival and neurological outcome in out-of-hospital cardiac arrest patients Read https://t.co/mSxMo7j3fL and thread ⤵️ https://t.co/8dT37xlE3S https://t.co/uhuGyk2vAN