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Mashup Score: 1
Purpose In patients with type 2 diabetes mellitus (T2DM), both sodium-glucose cotransporter 2 inhibitors (SGLT2is) and glucagon-like peptide receptor agonists (GLP-1 RAs) have demonstrated significant improvements in cardiovascular and kidney outcomes independent of their glycemic benefits. This paper will briefly compare the effect of SGLT2is and GLP-1 RAs to that of the SGLT1/2 inhibitor…
Source: Cardiovascular Drugs and TherapyCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 19
The chronic coronary syndromes (CCS) include patients with a classic history of angina pectoris in the presence of either risk factors for or known atherosclerotic coronary artery disease. Randomized, controlled trials conducted in the optimal medical therapy (OMT) era have convincingly demonstrated that adherence to the outdated paradigm focused on treatment of obstructive coronary disease with…
Source: Cardiovascular Drugs and TherapyCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 40
The chronic coronary syndromes (CCS) include patients with a classic history of angina pectoris in the presence of either risk factors for or known atherosclerotic coronary artery disease. Randomized, controlled trials conducted in the optimal medical therapy (OMT) era have convincingly demonstrated that adherence to the outdated paradigm focused on treatment of obstructive coronary disease with…
Source: Cardiovascular Drugs and TherapyCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 1Challenges in Optimizing Lipid Management in Women - Cardiovascular Drugs and Therapy - 3 year(s) ago
While there are physiologic differences in lipid metabolism in men and women, pharmacologic therapy is very effective in both with similar management strategies recommended in the current guidelines for the management of dyslipidemia. Despite similar guidelines for treatment, studies have shown that women have worse control of dyslipidemia than their male counterparts. This may stem from multiple…
Source: Cardiovascular Drugs and TherapyCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 3Electrical Stimulation for Low-Energy Termination of Cardiac Arrhythmias: a Review - Cardiovascular Drugs and Therapy - 3 year(s) ago
Cardiac arrhythmias are a leading cause of morbidity and mortality in the developed world, estimated to be responsible for hundreds of thousands of deaths annually. Our understanding of the electrophysiological mechanisms of such arrhythmias has grown since they were formally characterized in the late nineteenth century, and this has led to the development of numerous devices and therapies that…
Source: Cardiovascular Drugs and TherapyCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 1Electrical Stimulation for Low-Energy Termination of Cardiac Arrhythmias: a Review - Cardiovascular Drugs and Therapy - 3 year(s) ago
Cardiac arrhythmias are a leading cause of morbidity and mortality in the developed world, estimated to be responsible for hundreds of thousands of deaths annually. Our understanding of the electrophysiological mechanisms of such arrhythmias has grown since they were formally characterized in the late nineteenth century, and this has led to the development of numerous devices and therapies that…
Source: Cardiovascular Drugs and TherapyCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 3Electrical Stimulation for Low-Energy Termination of Cardiac Arrhythmias: a Review - Cardiovascular Drugs and Therapy - 3 year(s) ago
Cardiac arrhythmias are a leading cause of morbidity and mortality in the developed world, estimated to be responsible for hundreds of thousands of deaths annually. Our understanding of the electrophysiological mechanisms of such arrhythmias has grown since they were formally characterized in the late nineteenth century, and this has led to the development of numerous devices and therapies that…
Source: Cardiovascular Drugs and TherapyCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Five Years of Sacubitril/Valsartan—a Safety Analysis of Randomized Clinical Trials and Real-World Pharmacovigilance - 3 year(s) ago
Purpose In PARADIGM-HF, sacubitril/valsartan showed a significant reduction in mortality and hospitalization for patients with heart failure with reduced ejection fraction. Despite proven efficacy, sacubitril/valsartan has moderate uptake in clinical practice. This study explores the safety profile of sacubitril/valsartan by comparing adverse events in RCT and real-world use. Methods We studied…
Source: Cardiovascular Drugs and TherapyCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0Role of Bempedoic Acid in Clinical Practice - 3 year(s) ago
Many patients do not achieve optimal low-density lipoprotein cholesterol (LDL-C) levels with statins alone; others are unable to tolerate statin therapy. Additional non-statin treatment options including ezetimibe, proprotein convertase subtilisin/kexin type 9 inhibitors, and bile acid sequestrants are often necessary to further reduce the risk of atherosclerotic cardiovascular disease. This…
Source: Cardiovascular Drugs and TherapyCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0Thrombotic Complications in Patients with COVID-19: Pathophysiological Mechanisms, Diagnosis, and Treatment - 3 year(s) ago
Introduction Emerging evidence points to an association between severe clinical presentation of COVID-19 and increased risk of thromboembolism. One-third of patients hospitalized due to severe COVID-19 develops macrovascular thrombotic complications, including venous thromboembolism, myocardial injury/infarction and stroke. Concurrently, the autopsy series indicate multiorgan damage pattern…
Source: Cardiovascular Drugs and TherapyCategories: Cardiology News and Journals, Latest HeadlinesTweet
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