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Mashup Score: 0Implementing Precision Medicine Programs and Clinical Trials in the Community-Based Oncology Practice: Barriers and Best Practices - 2 year(s) ago
There has been a rapid uptick in the pace of oncology precision medicine advancements over the past several decades as a result of increasingly sophisticated technology and the ability to study more patients through innovative trial designs. As more precision oncology approaches are developed, the need for precision medicine trials is increasing in the community setting, where most patients with…
Source: ASCO Educational BookCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Implementing Precision Medicine Programs and Clinical Trials in the Community-Based Oncology Practice: Barriers and Best Practices - 2 year(s) ago
There has been a rapid uptick in the pace of oncology precision medicine advancements over the past several decades as a result of increasingly sophisticated technology and the ability to study more patients through innovative trial designs. As more precision oncology approaches are developed, the need for precision medicine trials is increasing in the community setting, where most patients with…
Source: ASCO Educational BookCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0
Pain remains common in the setting of malignancy, occurring as a consequence of cancer and its treatment. Several high-quality studies confirm that more than 50% of all patients with cancer experience moderate to severe pain. The prevalence of pain in cancer survivors is estimated to be 40%, while close to two-thirds of those with advanced disease live with pain. Progress has occurred in the…
Source: ASCO Educational BookCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0HER2 in Colorectal Cancer: The Long and Winding Road From Negative Predictive Factor to Positive Actionable Target - 3 year(s) ago
Human epidermal growth factor receptor 2 (HER2) is a well-known oncogenic driver in different tumors and an approved therapeutic target in breast and gastroesophageal cancer. In metastatic colorectal cancer, only 3% to 5% of patients present with HER2 alterations: somatic mutations and amplifications. HER2 was first assessed as a biomarker of resistance to anti-EGFR therapy; however, in more…
Source: ASCO Educational BookCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 2Innovative Approaches to the Management of Acute Lymphoblastic Leukemia Across the Age Spectrum - 3 year(s) ago
Adults compose nearly half of all patients diagnosed with acute lymphoblastic leukemia (ALL) and historically have had poor survival compared with pediatric patients. Recently approved therapies, such as monoclonal antibodies, CAR T-cell constructs, and next-generation tyrosine kinase inhibitors, have improved survival in relapsed and refractory ALL, and studies are now examining incorporating…
Source: ASCO Educational BookCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 2Management of Myeloproliferative Neoplasms in the Molecular Era: From Research to Practice - 3 year(s) ago
The 1960 discovery of the Philadelphia chromosome in chronic myeloid leukemia (CML) marked the beginning of the modern genomic era of oncology. In the following years, the molecular underpinnings of CML were unraveled, culminating in the development of the first molecularly targeted therapy: imatinib. Imatinib revolutionized CML management, inducing deep molecular responses for most patients and…
Source: ASCO Educational BookCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 4
Biochemical recurrence develops in almost one-third of men with prostate cancer after treatment with local therapy. There are numerous options for management, including surveillance, salvage radiation, androgen deprivation therapy (ADT), and clinical trials. This article reviews the current approaches to radiation therapy, ADT, and molecular imaging in men with biochemically recurrent prostate…
Source: ASCO Educational BookCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 3Strategies to Advance Equity in Cancer Clinical Trials - 3 year(s) ago
Cancer clinical trials are critical for testing new treatments, yet less than 5% of patients with cancer enroll in these trials. Minority groups, elderly individuals, and rural populations are particularly underrepresented in cancer treatment trials. Strategies for advancing equity in cancer clinical trials for these populations include (1) optimizing clinical trial matching by broadening…
Source: ASCO Educational BookCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 1Implementing Precision Medicine Programs and Clinical Trials in the Community-Based Oncology Practice: Barriers and Best Practices - 3 year(s) ago
There has been a rapid uptick in the pace of oncology precision medicine advancements over the past several decades as a result of increasingly sophisticated technology and the ability to study more patients through innovative trial designs. As more precision oncology approaches are developed, the need for precision medicine trials is increasing in the community setting, where most patients with…
Source: ASCO Educational BookCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 1Introducing Checkpoint Inhibitors Into the Curative Setting of Head and Neck Cancers: Lessons Learned, Future Considerations - 3 year(s) ago
The emergence of immunotherapy, in the form of immune checkpoint inhibitors, has irrevocably altered the paradigm of cancer treatment over the past decade. Multiple characteristics of the immune landscape in head and neck squamous cell carcinoma suggest a strong rationale for the use of immunotherapies in this disease. Data from studies with both single-agent immunotherapies and chemotherapy and…
Source: ASCO Educational BookCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
Implementing #PrecisionMedicine Programs and #ClinicalTrials in the Community-Based Oncology: Practice: Barriers and Best Practices [May 23, 2018] @JLErsek @lorablk @mtmdphd @DrEdKim #ASCO18 Educational Book https://t.co/UJqfs6bPXf https://t.co/zL49RwxYl7