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Vitamin D regulates microbiome-dependent cancer immunity
A role for vitamin D in immune modulation and in cancer has been suggested. In this work, we report that mice with increased availability of…
Vitamin D regulates microbiome-dependent cancer immunity
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Despite deep knowledge of how the immune system works, many questions remain difficult to answer within the current core framework of innate and adaptive immunity.…
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The gut microbiome associates with phenotypic manifestations of post-acute COVID-19 syndrome
Current understanding of the heterogeneity of post-acute COVID-19 syndrome (PACS) is limited. Examining the fecal microbiome in subjects with PACS, Su et al. uncover an association…
Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo
Nature – Topobiologically complex mini-colons—which enable the faithful in vitro recapitulation of colorectal cancer tumorigenesis and its environmental determinants—offer the…
Welcoming the Era of Gene Editing in Medicine | NEJM
Recent approvals of exa-cel for treatment of sickle cell disease and transfusion-dependent β-thalassemia mark the dawn of the era of gene editing in medicine. But…
Welcoming the Era of Gene Editing in Medicine | NEJM
Recent approvals of exa-cel for treatment of sickle cell disease and transfusion-dependent β-thalassemia mark the dawn of the era of gene editing in medicine. But…