Critical Care
A pioneering open access journal with a highly respected Editorial Board, Critical Care has been leading its field for more than a decade. The journal is …
Related Articles
Significance of critical closing pressures (starling resistors) in arterial circulation – Critical Care
Arterial pressure is the input pressure driving tissue blood flow. However, under most conditions organ blood flow is independent of arterial pressure. Tissue blood flow…
Impact of attaining aggressive vs. conservative PK/PD target on the clinical efficacy of beta-lactams for the treatment of Gram-negative infections in the critically ill patients: a systematic review and meta-analysis – Critical Care
Background To perform a systematic review with meta-analysis with the dual intent of assessing the impact of attaining aggressive vs. conservative beta-lactams PK/PD target on…
Outcome prediction of cardiac arrest with automatically computed gray-white matter ratio on computed tomography images – Critical Care
Background This study aimed to develop an automated method to measure the gray-white matter ratio (GWR) from brain computed tomography (CT) scans of patients with…
Characteristics, predictors and outcomes of new-onset QT prolongation in sepsis: a multicenter retrospective study – Critical Care
Background Sepsis-induced myocardial injury is a serious complication of sepsis. QT prolongation is a proarrhythmic state which reflects myocardial injury in a group of heterogeneous…
Use of artificial intelligence in critical care: opportunities and obstacles – Critical Care
Background Perhaps nowhere else in the healthcare system than in the intensive care unit environment are the challenges to create useful models with direct time-critical…
GFAP point-of-care measurement for prehospital diagnosis of intracranial hemorrhage in acute coma – Critical Care
Background Prehospital triage and treatment of patients with acute coma is challenging for rescue services, as the underlying pathological conditions are highly heterogenous. Recently, glial…
The management of heart failure cardiogenic shock: an international RAND appropriateness panel – Critical Care
Background Observational data suggest that the subset of patients with heart failure related CS (HF-CS) now predominate critical care admissions for CS. There are no…
“NeuroVanguard”: a contemporary strategy in neuromonitoring for severe adult brain injury patients – Critical Care
Severe acute brain injuries, stemming from trauma, ischemia or hemorrhage, remain a significant global healthcare concern due to their association with high morbidity and mortality…
Unraveling the role of HIF-1α in sepsis: from pathophysiology to potential therapeutics—a narrative review – Critical Care
Sepsis is characterized by organ dysfunction resulting from a dysregulated inflammatory response triggered by infection, involving multifactorial and intricate molecular mechanisms. Hypoxia-inducible factor-1α (HIF-1α), a…
Association between intensive care unit nursing grade and mortality in patients with cardiogenic shock and its cost-effectiveness – Critical Care
Background Despite the high workload of cardiac intensive care unit (ICU), there is a paucity of evidence on the association between nurse workforce and mortality…