• Mashup Score: 1

    Background SARS-CoV-2 infection leads to acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Both clinical data and animal experiments suggest that the renin–angiotensin system (RAS) is involved in the pathogenesis of SARS-CoV-2-induced ALI. Angiotensin-converting enzyme 2 (ACE2) is the functional receptor for SARS-CoV-2 and a crucial negative regulator of RAS. Recombinant…

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    • #CritCare #OpenAccess Recombinant #ACE2 plays a protective role against #SARS_CoV_2 lung injury https://t.co/WfbH5mvp0W @jlvincen @ISICEM #FOAMed #FOAMcc #BMC #ICU #rACE2 #pandemics #virus #spike_protein https://t.co/IIRovoP94w

  • Mashup Score: 1

    Resilience is ubiquitous in everyday speech, academic literature and governmental policies. Yet it seems to have taken a narrow scope in healthcare, confined to individual and psychological resilience. This short essay aims to broaden the understanding of resilience to organisational levels and calls intensivists to take active roles in fostering resilience for their staff. The article explores…

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    • #CritCare #OpenAccess Understanding RESILIENCE! https://t.co/Fybhx4Jcsp @jlvincen @ISICEM #FOAMed #FOAMcc #BMC #ICU #intensivists #healthcare_workers #BurnOut https://t.co/p8TZ8QJt86

  • Mashup Score: 3

    Background The purpose of this study was to clarify the prognostic value of Pentraxin-3 (PTX3) on the mortality of patients with sepsis. Methods Publications published up to January 2021 were retrieved from PubMed, EMBASE, and the Cochrane library. Data from eligible cohort and case–control studies were extracted for the meta-analysis. Multivariate regression analysis was used to evaluate the…

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    • #CritCare #OpenAccess The #prognostic value of #Pentraxin3 on the #mortality of patients with #sepsis https://t.co/zCtXhoK659 @jlvincen @ISICEM #FOAMed #FOAMcc #BMC #PTX3 #infection #inflammation #septic_shock #prevention https://t.co/nUu09MkhCP

  • Mashup Score: 2

    Background We determine the predictive value of transthoracic echocardiographic (TTE) metrics for clinical deterioration within 5 days in adults with intermediate-risk pulmonary embolism (PE). Methods This was a prospective observational study of intermediate-risk PE patients. To determine associations of TTE and clinical predictors with clinical deterioration, we used univariable analysis,…

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    • #CritCare #OpenAccess #Echocardiography predictors of clinical deterioration in adults with intermediate-risk #PulmonaryEmbolism https://t.co/ZpjscFaBfd @jlvincen @ISICEM #FOAMed #FOAMcc #BMC #ICU #RiskFactors #Lung #Embollism https://t.co/Tk8sR7dxLf