Short term complications of conisation and long term effects on fertility related outcomes in Denmark: register based nationwide cohort study
Objective To report on complications of conisation and its effects on fertility and stenosis. Design Register based nationwide cohort study on routinely collected data using several linked databases. Setting Primary and secondary care in Denmark, 2006-18. Population The conisation cohort comprised 48 048 conisations on women aged 23-65 who had undergone conisation within 120 days of a cervical biopsy. The biopsy cohort comprised 48 048 biopsies on women who had undergone a cervical biopsy but not conisation who were matched by age and time of procedure. Women were excluded from the conisation cohort before long term outcome analyses if they had undergone hysterectomy, resection of the uterus, or had cervical cancer or any long term outcomes within the 10 years before their conisation. Main outcome measures Bleeding, infection, and gynaecological operations within 30 days of conisation (stratified by age, year of conisation, and number of previous conisations) and long term risk of fert