Preventing ischemic heart disease in women: a systematic review of global directives and policies
npj Women’s Health – Preventing ischemic heart disease in women: a systematic review of global directives and policies
npj Women’s Health – Preventing ischemic heart disease in women: a systematic review of global directives and policies
Prostate-specific membrane antigen (PSMA) is a theranostic target for metastatic prostate cancer (PCa). However, castration-resistant PCa (CRPC) may lose PSMA expression after systemic therapy. Fibroblast…
There are high-level areas where nurses, once aware of the racial and ethnic disparities in hospice, can assist patients in receiving hospice services when appropriate.
Nature Communications – The authors explore sequence-encoded molecular grammar underlying the liquid liquid phase-separation of the human RNA polymerase II C-terminal domain and demonstrate that…
Nature Communications – Connexin 36 (Cx36) forms neuronal gap junctions essential for electrical synapses. Here, the authors reveal cryo-EM structures of human Cx36 bound to…
Nature Communications – GPCRs are vital drug targets. Here, authors use HDX-MS to gain insight into structural dynamics of β1AR upon ligand binding, revealing agonist-induced…
Nature Communications – Polyphosphate affects many cellular processes and is often found near cellular DNA. Here, the authors show that DNA forms shells around polyP-Mg2+…
Nature Communications – Cannabinoids potentiate responses of brain receptors, but their mechanism of action is unknown. Here, using coarse-grained MD simulations and electrophysiology of mutants,…
Nature Communications – KLHDC2 is a promising E3 ligase for targeted protein degradation (TPD). In this study, the authors demonstrate that heterobifunctional degraders induce cooperative…
Evidence Viral Infection Lingering in Human Body with Repercussions
Nature Communications – The µ-opioid receptor is a key clinical target. Here, the authors describe nanobody NbE, a selective and high affinity antagonist, which is…