Posters – ESMO Congress 2023
Marwan Fakih (Duarte, United States of America) We have previously reported significant differences between the tumor immune microenvironm ent (TIME) of primary colorectal cancer (CRC-P) and different metastatic sites. Increased immune cell infiltration, B-cells, and CD8 cells and decreased macrophages were noted in CRC-P and lung metastatic (LuM) lesions compared to liver (LM) and peritoneum (PM) metastases. We expanded our work to MSI CRC and compared their TIME to respective MSS tumor sites. De-identifi