One-Level Versus Two-Level Anterior Lumbar Interbody Fusion … : Spine
ries risk of complications including major vascular injury. Whether one-level and two-level ALIF offers similar outcomes is not known. Materials and Methods. Adults who underwent one-level L4-L5 or L5-S1 ALIF and two-level L4-S1 ALIF at a single academic institution were identified. Patient demographics, procedural characteristics, improvement in spinopelvic alignment, and one-year postoperative patient-reported outcome measures (PROMs) and complications were compared. Multivariate regression analyses, accounting for age, sex, and Charlson comorbidity index (CCI), were also performed. Results. In total, 158 ALIF patients (111 one-level and 47 two-level) were included, with mean age of 51.4 years, 57.0% female, mean CCI of 1.2, and mean follow-up of 27.0 months. Surgical time (147.3 vs. 124.6 min, P=0.002) and hospital length of stay (3.5 vs. 2.9 d, P=0.036) were higher for two-level ALIF. One-year postoperatively, two-level ALIF patients had more caudal apex of lordosis (P=0.016) an
