“If our results are confirmed in further studies, it would be relevant to screen for these resistance mutations already at diagnosis, and then consider other treatment options that could work better for patients with mutated tumors,” says Lao Saal, who led the study, the largest of its kind on resistance mutations in the estrogen receptor in primary breast cancer.
AbstractBackground. Despite their vital roles, informal caregivers of adult cancer patients are commonly overlooked in cancer care. This study describes pr
AbstractBackground. Racial and ethnic disparities in genomic testing could exacerbate disparities in access to precision cancer therapies and survival—part
AbstractBackground. To estimate the causal effect of surgery vs chemotherapy on survival in patients with T1-3NxM0 pancreatic cancer in a rigorous framewor
AbstractBackground. We conducted a systematic review and meta-analysis to examine outcomes of patients with endometrial intraepithelial neoplasia treated w
Abstract. During the COVID-19 pandemic, health systems, including federally qualified health centers, experienced disruptions in colorectal cancer (CRC) sc
The journal publishes manuscripts that describe new findings of particular significance across a full range of basic, clinical, and translational cancer researc
Abstract. During the COVID-19 pandemic, health systems, including federally qualified health centers, experienced disruptions in colorectal cancer (CRC) sc
AbstractBackground. It is unclear whether genetic variants affecting vitamin D metabolism are associated with melanoma prognosis. Two functional missense v
Abstract. Current evidence on de novo metastatic breast cancer is based on data from women. This Swedish population-based cohort study compared the inciden
AbstractBackground. Vaccination against human papillomavirus (HPV) is critical to the prevention of HPV-associated cancers. This study aimed to describe th
