Molecular Therapy_Emerging Diseases_Special Issue_2022
Molecular Therapy_Emerging Diseases_Special Issue_2022
Molecular Therapy_Emerging Diseases_Special Issue_2022
Cell Genomics provides an accessible forum for authors and is an indispensable resource for geneticists in all disciplines. In the run-up to receiving our first…
Cell Symposia: Engineering development and disease in organoids
Cas12a allows for easy multiplexing of guide RNAs in a single construct. CRISPRa, in which transactivation domains are used to overexpress endogenous genes, has been…
Generating brains from two different species via blastocyst complementation enables synchronous development of appropriate interspecies circuits. When host sensory neurons are disabled, donor neurons restore…
An optimized screening platform streamlined the identification of mutations that supported the generation of rat forebrain tissue in mice via interspecies blastocyst complementation.
Long-term ozone (O3) exposure may lead to non-communicable diseases and increase mortality risk. However, cohort-based studies are relatively rare, and inconsistent exposure metrics impair the…
Wu and colleagues report a robust and efficient protocol to generate human blastoids from naive PSCs and perform extensive characterization side-by-side with human blastocysts. The…
Read interviews with seven early career researchers, published in ASHG journals American Journal of Human Genetics and HGG Advances, who describe their career journeys, roadblocks,…
Histone deacetylases (HDACs) are important chromatin regulators essential for plant tolerance to adverse environments. In addition to histone deacetylation and epigenetic regulation, HDACs deacetylate non-histone…