Majara et al. show that polygenic scores generalize variably across diverse populations due to genetic differences between target and discovery cohorts. Multi-ancestry discovery GWAS typically improve prediction accuracy in underrepresented populations more than an increase in the European sample size, but not necessarily when sample sizes are imbalanced.
Milind Desai, MD describes favorable real-world safety outcomes from mavacamten use over 22 months of the Risk Evaluation and Mitigation Strategy (REMS) program.
The Tianhe Exa-node Prototype supercomputer has ranked first in Green Graph500’s big data category, achieving its second win since 2021.
Ochsner’s hospital-at-home pilot prevented either initial hospitalizations or 15-day readmissions for 92% of patients in the program.
Pertussis – a disease commonly referred to as whooping cough – is spreading quickly, the Centers for Disease Control and Prevention warns. The U.S. has seen…
Following the implementation of a new lung allocation system, Cleveland Clinic pulmonologists are working on further lowering waitlist times and patient mortality.
If you’ve hit a ”dink shot into the kitchen,” you know the joy of pickleball. Learn more about how the popular sport serves up lots…
This propulsion system would produce up to 100,000 N of thrust with a specific impulse (Isp) of 5,000 seconds.
Reflections on how growing up in Cold War Poland led Dr. Paluch to a career in science.
The first casualties of generative AI offer lessons for other businesses
