Large-Bore Mechanical Thrombectomy or Catheter-Directed Thrombolysis For Management of Intermediate-High–Risk Pulmonary Embolism – American College of Cardiology
Acute pulmonary embolism (PE) remains a diagnostic and therapeutic challenge, with an estimated 60,000-100,000 deaths each year in the United States. 1 Although the management of high-risk PE frequently involves systemic thrombolytics, the optimal approach for individuals at high risk who have contraindications to thrombolytics and those with intermediate-risk PE remains uncertain. In intermediate-risk PE, fibrinolytic therapy had lower rates of death or hemodynamic collapse than did standard anticoagulati
