It is unclear whether the effect of canagliflozin on adverse kidney and cardiovascular events in those with diabetic kidney disease varies by age and sex. We assessed the effects of canagliflozin among age group categories and between sexes in the Canagliflozin and Renal Endpoints in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) study.
Acute uncomplicated pyelonephritis is most commonly due to bacterial infection ascending from the lower urinary tract, and occurs more often in young adult women, 15…
A 47-year-old man with acute worsening of chronic diarrhea was admitted to the hospital with a serum creatinine of 2.2mg/dL from a baseline of 1.6mg/dL.…
Reasons for transfer from peritoneal dialysis (PD) to hemodialysis (HD) remain incompletely understood. Among incident and prevalent patients receiving PD, we evaluated the association between…
Chronic kidney disease (CKD) and acute kidney injury (AKI) are heterogeneous syndromes defined clinically by serial measures of kidney function. Each condition possesses strong histopathologic…
Acute kidney injury (AKI) is a common complication of cardiac surgery and its occurrence is associated with increased risk of all-cause mortality, adverse cardiovascular outcomes,…
Hemodialysis catheter dysfunction is an important problem for patients with kidney failure. The optimal design of the tunneled catheter tip is unknown. This study evaluated…
Studies have shown that generally healthy individuals who consume diets rich in plant foods have a lower risk of incident chronic kidney disease (CKD) and…
Improving the quality of care delivered to patients receiving maintenance dialysis and reducing their cost of care are central focuses for patients, providers, and payers.…
Toxic nephropathies are a clinically common group of disorders characterized by toxin-induced renal injury that can affect the glomerulus, vasculature, or tubulointerstitium. Various endogenous (eg,…
In this pilot study, we hypothesized that autosomal dominant polycystic kidney disease (ADPKD) is characterized by impaired kidney oxidative metabolism that associates with kidney size…
