“It’s a Trap”: Eosinophils Caught between Pro- and Anti-inflammatory Responses
Distinct from apoptosis or necrosis, eosinophil extracellular trap (ET) cell death (EETosis) is a deliberate form of cell death by which eosinophils unleash ETs (1). ETs are a dragnet of hypercitrullinated histones spangled with antimicrobial peptides and proteases and may be produced by several cell types in response to bacterial or fungal invaders (2). Eosinophil-derived ETs (EETs), however, are pathognomonic of several chronic nonallergic, noninfectious diseases. Intriguingly, EET preponderance is
