Is it Autumn for colchicine and osteoarthritis?

Colchicine is an ancient drug, derived from plants of the Colchicum variety (or Autumn Crocus). Mentioned in the Ancient Egyptian Ebers papyrus, colchicine was purified by the 18th century and has been in regular use by physicians ever since; it was finally licensed by the US Food and Drug Administration in 2009 for the prophylaxis and treatment of gout.1 Low doses of colchicine (0·5 mg two to…

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