To identify regulatory variants with plasticity in effect size, we performed interaction molecular quantitative trait loci (iQTL) mapping with cell-type abundance, age, sex, and smoking as the environmental factors. Our results highlight the usefulness of iQTLs for gaining insights into the context specificity of regulatory effects.
In this article, Thomaidou and colleagues show that miR-124 instructs the reprogramming switch of astrocytes toward an immature neuronal fate by targeting the RNA-binding protein…
The American Hospital Association wants the Biden administration to take immediate actions to increase the supply of IV solutions for hospitals, such as invoking the…
Experts are puzzling over which interventions are saving lives. The evolving illicit supply itself may hold important clues.
Program: Beyond Androgen Blockade – New Pathways and Novel Treatments in mHSPC and mCRPC Part of an Independent Medical Education Initiative Supported by LOXO@Lilly Biographies:…
Upcoming data from a mid-stage study of Amgen’s experimental weight-loss drug MariTide will shed light on how well it might measure up against the popular…
IVC filters, implants that prevent blood clots, aren’t meant to be permanent — but doctors often forge to retrieve them.
Hänggi et al. investigate how tumor necroptosis regulates anti-tumor immunity and find an unexpected role for interleukin-1α (IL-1α) release by dying cells in promoting tumor growth…
Trump’s #tariffs could raise the cost of medical care and prescription drugs for people in the U.S.
The film, “The M Factor: Shredding the Silence on Menopause,” is accredited for physicians
This collection emphasizes how our understanding of cell death is constantly evolving and underlines the importance of molecular pathways in the context of development and…
