Immunosuppressive Therapy Reversing Obstructive Hydrocephalus in CLIPPERS | Neurology
A 32-year-old woman presented with subacute dizziness, dysarthria, and unsteady gait, accompanied by progressive headache and memory loss. No facial paresthesia, diplopia, or urinary incontinence was reported. MRI showed obstructive hydrocephalus, diffuse cerebellar swelling with vasogenic edema, and “pepper-like” speckle, curvilinear enhancing lesions predominantly in the cerebellum (Figure 1, A–H). CSF analysis revealed normal protein (29 mg/dL), white blood cell count (5 cells/µL), and negative