The development of checkpoint antibodies for cancer therapy has been guided by the principle of blocking T cell inhibitory signals. Recognition of the role of the Fc domain in therapeutic activities, through the depletion of immunosuppressive populations and myeloid cell activation, prompts a shift toward the development of optimized Fc-engineered checkpoint antibodies.
Clinical Hematology International is an open-access journal supported by the International Academy for Clinical Hematology
The ESMO Manifesto represents the Society’s commitment to support European institutions as well as national decision-makers
At least three trusts have efficiency targets approaching 10 per cent of their budget this year, HSJ research has found.
Government plan to reduce smoking rates in danger of falling a decade behind schedule
Some consultants are being paid £200 an hour for working extra hours, a BBC News investigation finds.
Class was once a strong indicator of which political party you would support. But since 2001, something quite different has been happening.
If you didn’t forget things, you’d be in for a world of trouble.
A survey of 1,000 UK doctors found one in five used ChatGPT or Gemini in clinical practice.
Abstract. Precision oncology tailors treatment strategies to a patient’s molecular and health data. Despite the essential clinical value of current diagnostic methods, hematoxylin and eosin…
