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American College of CardiologyA single dose of tranexamic acid (TXA) at the beginning and end of surgery significantly reduced major bleeding in patients undergoing noncardiac surgery compared with placebo, based on findings from the POISE-3 trial presented April 2 at ACC.22 and simultaneously published in the New England Journal of Medicine. The study randomized 9,535 patients undergoing noncardiac surgery at 114...
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