Fatal late-onset CAR T-cell–mediated encephalitis after axicabtagene-ciloleucel in a patient with large B-cell lymphoma | Blood Advances | American Society of Hematology

A frightening case report of a fatal case of neurotoxicity 8 months after Axi-Cel infusion. CAR-T cells were found in post-mortem brain tissue suggest direct CAR-T related toxicity. This case highlights the importance of ICANS and the need for better treatment and understanding of this toxicity.

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