Key Points. Fatal neurotoxicity developed 9 months after infusion of axi-cel in a patient treated for diffuse LBCL relapse after allogeneic hematopoietic cell t
A frightening case report of a fatal case of neurotoxicity 8 months after Axi-Cel infusion. CAR-T cells were found in post-mortem brain tissue suggest direct CAR-T related toxicity. This case highlights the importance of ICANS and the need for better treatment and understanding of this toxicity.