In a significant leap forward for personalized cancer treatments, scientists at PACT Pharma and the University of California, Los Angeles, have demonstrated the feasibility of isolating and cloning multiple TCRs that detect patients’ cancer cells, simultaneous knocking-out of endogenous TCRs and knocking-in of neoTCRs using precision genome editing, manufacturing edited T cells at clinical grade,…
SCG says it has developed in-house cGMP manufacturing capabilities to supply high-quality cell therapy products to patients.
And there are benefits of plant cell expression systems, notably their impact on the cost of goods sold (COGS).
A British-based cell therapy company is using smart operations to streamline its viral vector processing.
CMS proposed Medicare’s CGT reimbursement policy matches Medicaid’s sickle cell disease policy, forming a unified government approach.
Prodigiosin applications extend from manufacturing pigment and environmental-control agent to antibiotic and potential oncology drug.
Insilico Medicine is heading to the clinic with a treatment for methylthioadenosine phosphorylase (MTAP) deleted cancers.
New data-intensive platforms continue to leverage artificial intelligence tools for improved speed and failure rate reductions for drug discovery.
The mini colons replicate both the physical structure and cellular diversity in the colon in both healthy and diseased states.
Regeneron Pharmaceuticals will use Mammoth Biosciences’ CRISPR-based ultracompact gene editing platform to develop in vivo therapies for tissues and cell types beyond the liver.
Workflow design and data management are pivotal components of cell and gene therapy research and development. Advances in artificial intelligence, informatics, and automation have made…
