COVID drug Paxlovid was hailed as a game-changer. What happened?
Insufficient investment and fears about rebound and side effects are driving down use of a lifesaving antiviral.
Insufficient investment and fears about rebound and side effects are driving down use of a lifesaving antiviral.
Nature Reviews Nephrology – Clinical algorithms that are used to guide medical decision-making often include sex as a variable. However, binary considerations of sex and/or…
Denial and a lack of unity across states are limiting a swift response to the novel outbreak
Nature Communications – CDK4/6 inhibitors have improved outcomes for patients with ER+ breast cancer, however, those with loss of RB1 function often fail to respond.…
Nature Electronics – Photo-responsive metal halide perovskite light-emitting diodes can be used to create a multifunctional display that can function as a touch screen, ambient…
Nature Reviews Gastroenterology & Hepatology – Pouchitis is a common condition that can occur after intestinal surgery. In this Review, Shen discusses our current understanding…
Nature – Topobiologically complex mini-colons—which enable the faithful in vitro recapitulation of colorectal cancer tumorigenesis and its environmental determinants—offer the…
Nature – HRO761 is a potent, selective, allosteric WRN inhibitor that binds at the interface of the D1 and D2 helicase domains, locking WRN in…
Veterinarians and researchers on the front lines say it has taken too long to share data on viral changes, spread, and milk safety
Nature – Tiny 3D structures made from human stem cells sometimes offer insights that animal models cannot.
Blood Cancer Journal – Daratumumab-based quadruplet therapy for transplant-eligible newly diagnosed multiple myeloma with high cytogenetic risk