Contents | Science Immunology 9, 94
ONLINE COVER Cultivating Memory B Cell Responses to a Plant-Based Vaccine. CoVLP (coronavirus virus-like particle) is a promising COVID-19 vaccine produced in the weed Nicotiana benthamiana. A squalene-based adjuvant, AS03, can enhance immune responses to CoVLP vaccination, but how AS03 affects memory B cell responses to CoVLP is unknown. Grigoryan et al. studied immune responses in healthy individuals who received two doses of CoVLP with or without AS03. They found that AS03 promoted the progressive