Centrally Acting ACE Inhibitor Use and Physical Performance in Older Adults – The Journal of Frailty & Aging

Background There is conflicting evidence regarding the role of angiotensin-converting enzyme inhibitors and physical function. While some studies show improvements in muscle strength and physical function, others show no significant difference or decreased performance. This ambiguity could be due to differential effects of angiotensin-converting enzyme inhibitor subtypes which can be categorized…

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Source: SpringerLink

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George, C.J., Hall, C.B., Weiss, E.F. et al. Centrally Acting ACE Inhibitor Use and Physical Performance in Older Adults. J Frailty Aging 12, 103–108 (2023). https://t.co/bpB4sNCHt8

Bempedoic Acid: A Contemporary Review of Its Pharmacology, Efficacy, and Safety Profile, Including Recent Data from the CLEAR Outcomes Clinical Trial – Current Cardiology Reports

Purpose of Review To provide an updated review of bempedoic acid’s clinical application in lowering LDL-C in the setting of statin intolerance and the recent…

National Lipid Assoc October 5, 2023

Is Metabolic Surgery Having an Identity Crisis? – Obesity Surgery

Obesity Surgery –

Neil Floch MD August 16, 2023

Intrahepatic Balloon Tamponade for Penetrating Liver Injury: Rarely Needed but Highly Effective – World Journal of Surgery

Background Severe penetrating liver injuries are associated with high rates of morbidity and mortality. The objective of this study was to demonstrate the 15-year experience…

Elliott R Haut, MD, PhD August 10, 2023

Belzutifan in adults with VHL-associated central nervous system hemangioblastoma: a single-center experience – Journal of Neuro-Oncology

Purpose Belzutifan is a selective inhibitor of hypoxia-inducible factor 2 alpha (HIF-2a) that has emerged as a targeted therapy option for Von Hippel–Lindau (VHL) syndrome-associated…

Journal of Neuro-Oncology August 2, 2023

Performance Adaptations to Intensified Training in Top-Level Football – Sports Medicine

Because physical demands are surging in football (soccer, USA), clubs are more and more seeking players who have a high capacity to perform repeated intense…

Sports Medicine July 30, 2023

Improvement in visual outcomes of patients with base of skull meningioma as a result of evolution in the treatment techniques in the last three decades: a systematic review – Journal of Neuro-Oncology

Purpose We systematically reviewed visual outcomes over the last three decades in patients undergoing treatment for base of skull (BOS) meningiomas and provide recommendations to…

Journal of Neuro-Oncology July 18, 2023

The role of vaccines in the COVID-19 pandemic: what have we learned? – Seminars in Immunopathology

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged late in 2019 and caused the coronavirus disease 2019 (COVID-19) pandemic that has so far claimed approximately…

Florian Krammer July 18, 2023

Prospective phenotyping of CHAMP1 disorder indicates that coding mutations may not act through haploinsufficiency – Human Genetics

CHAMP1 disorder is a genetic neurodevelopmental condition caused by mutations in the CHAMP1 gene that result in premature termination codons. The disorder is associated with…

Medical Xpress July 18, 2023

In vivo quantitative MRI: T1 and T2 measurements of the human brain at 0.064 T – Magnetic Resonance Materials in Physics, Biology and Medicine

Objective To measure healthy brain $${T}_{1}$$ T 1 and $${T}_{2}$$ T 2 relaxation times at 0.064 T. Materials and methods $${T}_{1}$$ T 1 and $${T}_{2}$$…

Medical Xpress July 17, 2023

Diabetes precision medicine: plenty of potential, pitfalls and perils but not yet ready for prime time – Diabetologia

Rapid advances in technology and data science have the potential to improve the precision of preventive and therapeutic interventions, and enable the right treatment to…

Ash Paul July 17, 2023

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