Caveolin-1 Scaffolding Domain Peptide (CSP7): A Novel Target for Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is characterized by scarring, thickening of lung tissue, and persistent alveolar destruction. This is, in part, contributed by the apoptosis and senescence of alveolar epithelial cells (AECs), leading to the disappearance of alveolar epithelium (1). Histologically, the distinctive feature of IPF includes an increased proliferation of AECs; increased macrophages, fibroblasts, myofibroblasts; and a significant extracellular matrix deposition that is associated with
