Aortic Stenosis With Dynamic Left Ventricular Outflow Obstruction: Diagnostic and Management Challenges—A Case Series
Although rare, aortic valve stenosis (AS) can coexist with hypertrophic cardiomyopathy (HCM) with obstruction. In an estimate from 207,880 patients from the National Inpatient Sample who underwent transcatheter aortic valve (AV) implantation from 2014 to 2018, about 0.38% had concomitant HCM.1 When these two entities are coexistent, diagnosis and management becomes extremely difficult, as conventional assessment of AS may be inaccurate because of the presence of serial stenoses.2-4 Current guidelines provide a framework for delineating the driving pathology when encountering patients with both of these conditions, though applying these principles to real-world practice remains challenging.