Addition of veliparib to temozolomide fails to extend survival in glioblastoma
The addition of veliparib to adjuvant temozolomide failed to improve OS for patients with newly diagnosed, MGMT-hypermethylated glioblastoma, according to randomized phase 2/phase3 study results.Patients assigned the investigative combination achieved a 3.3-month improvement in median OS; however, the difference did not reach statistical significance.