A TH17-intrinsic IL-1β–STAT5 axis drives steroid resistance in autoimmune neuroinflammation
IL-1β mediates steroid resistance in TH17 cells via a STAT5-dependent mechanism during autoimmune CNS inflammation.
IL-1β mediates steroid resistance in TH17 cells via a STAT5-dependent mechanism during autoimmune CNS inflammation.
The health risks of social isolation and loneliness are inspiring government action and a hunt for effective interventions
“A blog about allergy, asthma & immunology”
Despite identifying El Niño events as a factor in dengue dynamics, predicting the oscillation of global dengue epidemics remains challenging. Here, we investigate climate indicators…
Neurodegenerative disorders present major challenges to global health, exacerbated by an aging population and the absence of therapies. Despite diverse pathological manifestations, they share a…
Intrinsic and innate immune responses are essential lines of defense in the body’s constant surveillance of pathogens. The discovery of liquid–liquid phase separation (LLPS) as…
The humoral arm of mammalian innate immunity regulates several molecular mechanisms involved in resistance to pathogens, inflammation, and tissue repair. Recent studies highlight the crucial…
One of the biggest issues particularly impacting patients with respiratory diseases is climate change. A recent paper published in Frontiers in Science demonstrated that multiple…
Edible gel reduces blood alcohol levels in inebriated mice