Optimal first-line therapy for unresectable melanoma in-transit metastases has not been established, and options include isolated limb infusion/perfusion, immune checkpoint inhibitors, and intralesio…
A combination of immunological reaction to a drug and HHV-6 reactivation results in the severe course of DIHS. The demonstration of HHV-6 reactivation is a…
Purpose: We describe the impact of screening on outcomes of patients diagnosed with hepatocellular carcinoma (HCC) in an urban safety-net healthcare system compared to a…
Primary Myelofibrosis previously also known as Agnogenic Myeloid Metaplasia or Idiopathic Myelofibrosis is a complex myeloproliferative disease. Although the initial genetic insult that causes uncontrolled…
Acute myelopathy is a rare but devastating complication of chimeric antigen receptor (CAR) T-cell therapy for patients with hematological malignancies. Des
Key PointsEMD mimics the architectural complexity of solid tumors, marked by diverse microenvironments, multiclonality, and TNFRSF17 and GPRC5D levels.EMD
Abstract. Purpose: Pancreatic adenocarcinoma (PDAC) has limited treatment options. We compared the efficacy of comprehensive precision medicine against the conventional treatment in PDAC. Methods: Phase…
Chimeric antigen receptor-T cell (CAR-T) therapy has transformed the management of refractory hematological malignancies. Now that targeting pathogenic cells of interest with antigen-directed cytotoxic T…
For more than 50 years, through successive iterations of regimens incorporating alkylating agents, anthracyclines, and taxanes, adjuvant cytotoxic chemotherapy has improved the prognosis of patients…
Background and ObjectivesEnhanced communication has been recognized as an effective strategy to improve patient safety and care quality. While some communication skills can be taught…
