Participant Protection in Phase 1 Pediatric Cancer Trials
This Viewpoint describes changes in the regulatory environment for phase 1 research involving children and discusses improvements to patient protection.
This Viewpoint describes changes in the regulatory environment for phase 1 research involving children and discusses improvements to patient protection.
This Viewpoint examines whether overdiagnosis rather than underdiagnosis may now be the dominant form of myocardial infarction misdiagnosis.
This cross-sectional study investigates the association between cardiometabolic disease prevalence in the US and deep learning–based assessment of the built environment from satellite imagery.
This cohort study explores whether a novel artificial intelligence (AI) video-based biomarker for aortic stenosis is associated with development and progression of aortic stenosis.
This survey study reports on use of renal replacement therapy, hemodynamic support, sedation, neuroimaging, and extracorporeal membrane oxygenation at Renal Anhydramnios Fetal Therapy trial sites…
This cross-sectional study evaluates emergency department visits for physical injuries from use of conducted energy devices by police departments.
This cross-sectional study investigates the stroke burden trends in the US in 2019 and how they evolved from 1990 to 2019 with a focus on…
This cross-sectional study evaluates the use of the US Food and Drug Administration’s Real-Time Oncology Review (RTOR) program in confirming the effectiveness of cancer drugs.
This randomized clinical trial investigates the effects of solanezumab and ganterenumab on downstream biomarkers in individuals with dominantly inherited Alzheimer disease.
This cohort study examines the rates of toxic effects following cancer treatment with high-field magnetic resonance–guided radiotherapy, in particular online adaptive workflows in which the…
This JAMA Insights discusses the adverse effects of climate change on mental health and proposes solutions to help mitigate those effects.