Neuregulin 1 (NRG1) fusions are recurrent oncogenic drivers found in multiple solid tumors. NRG1 binds to human epidermal growth factor receptor 3 (HER3), leading to heterodimerization with HER2 an…
Premature death is common among people experiencing homelessness. The profound neglect that people who are homeless experience in life is just as tragic in death.
PURPOSEImmunoscore (IS) and circulating tumor DNA (ctDNA) are two emerging technologies in improving prognostication and tailoring adjuvant treatments in patients resected from a stage III…
Whether fixed-duration acalabrutinib–venetoclax (with or without obinutuzumab) would result in better progression-free survival than chemoimmunotherapy in patients with untreated chronic lymphocyti…
Senate leaders renew push on reimbursement rates for primary care doctors, saying many patients can’t find a doctor.
HLH, a cytokine-mediated hyperinflammation syndrome, causes fever, pancytopenia, and hemophagocytosis and is often fatal. Antiinflammatory agents, etoposide, and interferon-γ antibody are the main …
Do you feel sleepy during the day? Doze off and let’s hope it’s not while you are driving? Does your bed partner wake up when…
Since the Industrial Revolution, normal body temperature in both men and women has decreased monotonically by 0.03°C per birth decade.
Malignant T-cell transformation after chimeric antigen receptor (CAR) T-cell therapy has been described, but the contribution of CAR integration to oncogenesis is not clear. Here…
Nature – Applying natural language processing to health records generates a data set that can be used to predict cancer outcomes.
Nature – PELO–HBS1L and SKI complexes in the human mRNA quality control pathway exhibit a synthetic lethal interaction and may represent novel targets for the…
