Electrical substrate of the right ventricle in valvular pulmonary stenosis: Early observations from electrophysiology studies before pulmonary valve replacement
Infants with severe valvular pulmonary stenosis (PS) are palliated by transcatheter balloon pulmonary valvuloplasty or surgical pulmonary valvotomy. Either strategy effectively relieves the obstruction, but 1 long-term sequela is pulmonary regurgitation (PR) necessitating pulmonary valve replacement. The introduction of transcatheter self-expanding platforms, such as the Harmony transcatheter pulmonary valve (Medtronic Inc, Minneapolis, MN) and the Alterra adaptive prestent (Edwards Lifesciences, Irvine, CA), has significantly increased the number of patients with native right ventricular outflow tract (RVOT) dysfunction eligible for transcatheter pulmonary valve replacement (TPVR).
