Effect of Helmet Ventilation vs High-Flow Nasal Oxygen on Need for COVID-19 Respiratory Support

This randomized trial compares the effects of helmet noninvasive ventilation (≥48 hours) followed by high-flow nasal oxygen (HFNO) vs HFNO alone on the number of days free of respiratory support at 28 days among patients with COVID-19 and moderate to severe hypoxemia.

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