2025 February Author Interview-Xue Xiao and Feifan Chen
Drs Xue Xiao and Feifan Chen discuss their article, “Application of endoscopic purse-string sutures in refractory nonvariceal GI bleeding: a multicenter stud…
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The Lancet Gastroenterology and Hepatology: Homepage
Discover articles from The Lancet Gastroenterology & Hepatology, providing a clear, independent perspective about the clinical advances and practice-changing research shaping your specialty globally
Single-cell omics in inflammatory bowel disease: recent insights and future clinical applications
Inflammatory bowel diseases (IBDs), which include ulcerative colitis (UC) and Crohn’s disease (CD), are chronic conditions characterised by inflammation of the intestinal tract. Alterations in…
Tell Me Again About the “Physician Shortage”
Everyone knows there’s a doctor shortage, right? Wait times are long. Visits are short. And that’s if you can even find a doctor that takes…
How to identify a heart attack in women
February is Women’s Heart Disease Awareness month. Heart disease is the number one killer of women in the U.S. and worldwide. Learn how to identify…
Surveillance in inflammatory bowel disease: white light endoscopy with segmental re-inspection versus dye-based chromoendoscopy – a multi-arm randomised controlled trial (HELIOS)
Background It remains unclear if the increased colorectal neoplasia detection rate in inflammatory bowel disease (IBD) by high-definition (HD) dye-based chromoendoscopy compared with HD white-light…
Glucocorticoid receptor suppresses GATA6-mediated RNA polymerase II pause release to modulate classical subtype identity in pancreatic cancer
Background Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer with a 5-year survival rate of 12%. It has two major molecular subtypes: classical and…
Glutamine metabolic competition drives immunosuppressive reprogramming of intratumour GPR109A+ myeloid cells to promote liver cancer progression
Objective The metabolic characteristics of liver cancer drive considerable hurdles to immune cells function and cancer immunotherapy. However, how metabolic reprograming in the tumour microenvironment…
Novel hemostatic adhesive powder to prevent delayed bleeding after endoscopic submucosal dissection in the GI tract: first U.S. multicenter experience
Post written by Maham Hayat, MD, and Dennis Yang, MD, from the Center for Interventional Endoscopy, AdventHealth, Orlando, Florida, USA. This study aimed to evaluate the use of …
Emerging role of environmental pollutants in inflammatory bowel disease risk, outcomes and underlying mechanisms
Epidemiological and translational data increasingly implicate environmental pollutants in inflammatory bowel disease (IBD). Indeed, the global incidence of IBD has been rising, particularly in developing…