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Mashup Score: 9Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 - 1 hour(s) ago
Globally, life expectancy and age-standardised disease burden were forecasted to improve between 2022 and 2050, with the majority of the burden continuing to shift from CMNNs to NCDs. That said, continued progress on reducing the CMNN disease burden will be dependent on maintaining investment in and policy emphasis on CMNN disease prevention and treatment. Mostly due to growth and ageing of populations, the number of deaths and DALYs due to all causes combined will generally increase. By constructing alternative future scenarios wherein certain risk exposures are eliminated by 2050, we have shown that opportunities exist to substantially improve health outcomes in the future through concerted efforts to prevent exposure to well established risk factors and to expand access to key health interventions.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 2Inflammatory bowel disease has no borders: engaging patients as partners to deliver global, equitable and holistic health care - 4 hour(s) ago
World inflammatory bowel disease (IBD) Day 2024 unites around the theme IBD has no borders. As a multinational authorship of physicians and people with lived experiences of IBD, we recognise that Crohn’s disease and ulcerative colitis extend across both geographical and personal boundaries. Traditionally considered to be a disease of high-income countries (HICs), IBD today is a global condition with an accelerated incidence in Asia, Africa, and Latin America, which parallels industrialisation and lifestyle change.
Source: www.thelancet.comCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 201Stop the Gaza genocide immediately - 10 hour(s) ago
Since the attacks by Hamas against Israel on Oct 7, 2023,1 the Israeli retaliatory strikes, bombings, and strict sieges have almost never stopped. So far, more than 85% of Gaza’s population have been displaced,2 and as of April 13, 2024, at least 33 000 Palestinians have been killed (more than a third of them are children)3 and 70 000 civilians have been injured.4 Approximately 7000 Palestinians are reportedly missing—most are likely dead.3,4 This massacre has taken place in just 180 days and is still ongoing.
Source: www.thelancet.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 315Ending plastic pollution: an opportunity for health - 13 hour(s) ago
In the far future, when the human species is extinct and every ruin has long since crumbled, the last remaining sign of our civilisations might well be a distinct layer of plastics in the geological strata. The Anthropocene can be defined by plastic: cheap, convenient, incredibly durable, and endlessly adaptable, it is a wonder material. There is much good that comes from plastic. 21st century medicine would be unimaginable without it: from intravenous tubes to gowns; syringes to catheters. Plastics have become integral to modern life.
Source: www.thelancet.comCategories: General Medicine News, Expert PicksTweet
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Mashup Score: 9Findings from the Global Burden of Disease Study 2021 - 17 hour(s) ago
In The Lancet, we have published the findings of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 in a series of six Articles.1–6 GBD began in 1991 and has continued over the past three decades to provide a comprehensive empirical assessment of health around the world.7 With each iteration GBD has become more detailed, including more causes, risks, and locations, improving granularity of age group analyses, and has enabled the completion of extension studies, such as forecasting studies and estimations of the burden of antimicrobial resistance.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 38Invasive liver abscess syndrome with central nervous system involvement caused by hypermucoviscous Klebsiella pneumoniae: positive string test - 18 hour(s) ago
A 57-year-old woman with a 3-day history of abdominal pain, vomiting, diffuse myalgia, and a temperature peaking at 39°C presented to her local hospital. The patient had a medical history of hypertension and type 2 diabetes and was prescribed losartan and metformin.
Source: www.thelancet.comCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 12Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open label, phase 3 superiority trial - 19 hour(s) ago
There was no benefit and possible harm from treatment with intravenous tenecteplase. Patients with minor stroke and intracranial occlusion should not be routinely treated with intravenous thrombolysis.
Source: www.thelancet.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 36
SGLT2 inhibitors reduced heart failure events and cardiovascular death in patients with heart failure, type 2 diabetes, chronic kidney disease, and atherosclerotic cardiovascular disease. These effects were consistent across a wide range of subgroups within these populations. This supports the eligibility of a large population with cardiorenal-metabolic diseases for treatment with SGLT2 inhibitors.
Source: www.thelancet.comCategories: General Medicine News, EndocrinologyTweet
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Mashup Score: 3
Although more participants who were assigned specialist physiotherapy self-rated their motor symptoms as improved and had better scores on subjective measures of mental health, the intervention did not result in better self-reported physical functioning at 12 months. Both the specialist and community neurological physiotherapy appeared to be a safe and a valued treatment for selected patients with functional motor disorder. Future research should continue to refine interventions for people with functional motor disorder and develop evidence-based methods to guide treatment triage decisions.
Source: www.thelancet.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 26Using AI to bridge global surgical gaps: high tech, high impact - 20 hour(s) ago
The Lancet Commission on global surgery reported that the poorest third of the world’s population undergoes just 6% of the approximately 313 million major operations performed annually.1 This gap not only denotes vast morbidity and millions of potentially preventable deaths, but also highlights deep-rooted global surgical inequities. Compounded by the challenges of the COVID-19 pandemic,2 these inequities necessitate an immediate, concerted call to action.
Source: www.thelancet.comCategories: General Medicine News, General HCPsTweet
Global life expectancy to increase by nearly 5 years by 2050 despite geopolitical, metabolic, and environmental threats, reports new global @TheLancet study. https://t.co/WfiAr4NdUS https://t.co/tXMornJrGC