When is crossover desirable in cancer drug trials and when is it problematic?
Journal List Ann Oncol PMC5961160 Ann Oncol. 2018 May; 29(5): 1079–1081. The use of crossover, as a design feature of randomized trials, is common, with…
Journal List Ann Oncol PMC5961160 Ann Oncol. 2018 May; 29(5): 1079–1081. The use of crossover, as a design feature of randomized trials, is common, with…
Mandrola and Prasad are back
Mandrola and Prasad are back
Vinay Prasad, MD MPH; Physician & Professor Hematologist/ OncologistProfessor of Epidemiology, Biostatistics and MedicineAuthor of 450+ Peer Reviewed papers,…
The phase 3 PROfound trial led to the recent approval of the PARP inhibitor olaparib for men with metastatic castration-resistant prostate cancer and mutations in…
Cancer is deadly, but 68% of the drugs approved by FDA have no evidence they increase survival!
It does the least harm to kids and adults
This review of approvals of cancer drugs based on a surrogate end point by the US Food and Drug Administration assesses the postmarketing findings for…
Cancer Medicine is an open access, broad-scope oncology journal covering clinical cancer research, cancer biology, cancer prevention, & bioinformatics.