What’s the Best Temperature for Sleep?
Is it better to sleep in cooler or warmer temperatures? A sleep psychologist shares how both can affect our REM cycles and overall health.
Is it better to sleep in cooler or warmer temperatures? A sleep psychologist shares how both can affect our REM cycles and overall health.
Explore special articles published online first to coincide with presentations at the American Psychiatric Association Annual Meeting.
Allosteric modulation of pentameric ligand-gated ion channels (pLGICs) is critical to the action of neurotransmitters and many psychoactive drugs. However, details of their modulatory mechanisms…
Homotropic cooperativity is widespread in biological regulation. The homo-oligomeric ring-shaped trp RNA binding attenuation protein (TRAP) from bacillus binds multiple tryptophan ligands (Trp) and becomes…
Information processing in the human brain can be modelled as a complex dynamical system operating out of equilibrium with multiple regions interacting nonlinearly. Yet, despite…
High-resolution epitope mapping is important for in-depth activity assessment of antibodies and understanding of their functions, however, glycosylated antigens are challenging for many methods including…
In vitro colonies of the flagellated parasite Trypanosoma brucei grow in characteristic fingering instability patterns. The underlying cause of this this type of collective migration…
Third-harmonic generation microscopy is a powerful label-free nonlinear imaging technique, providing essential information about structural characteristics of cells and tissues without requiring external labelling agents.…
Most fish species are ectothermic and rely on behavioral strategies to control their body temperature in heterothermal environments. Both thermotaxis and thermokinesis have been suggested…
DNA cytosine methylation is an epigenetic marker which regulates many cellular processes. Mammalian genomes typically maintain consistent methylation patterns over time, except in specific regulatory…
Autologous photoreceptor cell replacement therapy shows great promise for treating patients with multiple forms of inherited retinal degenerative blindness. Specifically, in disorders such as retinitis…