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Mashup Score: 20Do goals of care documentation reflect the conversation?: Evaluating conversation‐documentation accuracy - 28 day(s) ago
Journal of the American Geriatrics Society (JAGS) is the go-to geriatrics journal for clinical aging research including education, clinical practice and public policy.
Categories: General Medicine News, Hem/OncsTweet
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Mashup Score: 18Clinical Benefit and Regulatory Outcomes of Cancer Drugs Receiving Accelerated Approval - 1 month(s) ago
This study aims to determine whether cancer drugs granted accelerated approval from the US Food and Drug Administration ultimately demonstrate clinical benefit and to evaluate the basis of conversion to regular approval.
Source: jamanetwork.comCategories: General Medicine News, Oncologists1Tweet
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Mashup Score: 18Clinical Benefit and Regulatory Outcomes of Cancer Drugs Receiving Accelerated Approval - 1 month(s) ago
This study aims to determine whether cancer drugs granted accelerated approval from the US Food and Drug Administration ultimately demonstrate clinical benefit and to evaluate the basis of conversion to regular approval.
Source: jamanetwork.comCategories: General Medicine News, Oncologists1Tweet
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Mashup Score: 18Prevalence and Cancer-Specific Patterns of Functional Disability Among US Cancer Survivors, 2017-2022 - 1 month(s) ago
PURPOSE To examine the prevalence and cancer-specific patterns of functional disabilities among US cancer survivors. METHODS Data from 47,768 cancer survivors and 2,432,754 noncancer adults age 18 years and older from the 2017 to 2022 Behavioral Risk Factor Surveillance System were analyzed. Functional disabilities assessed included mobility disability (ie, serious difficulty walking or climbing stairs) and self-care disability (ie, self-reported difficulty dressing or bathing). Multivariable logistic regression models were used to assess the associations between functional disabilities and sociodemographic, lifestyle, and health-related factors. RESULTS Cancer survivors tended to be older and non-Hispanic White than noncancer adults. The prevalence of mobility disability (27.9% v 13.4%) and self-care disability (7.4% v 3.8%) were higher among cancer survivors compared with noncancer adults. After multivariable adjustments, cancer survivors were more likely to report mobility (odds rat
Source: ascopubs.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 11National Estimates of the Participation of Patients With Cancer in Clinical Research Studies Based on Commission on Cancer Accreditation Data - 1 month(s) ago
PURPOSE National estimates of cancer clinical trial participation are nearly two decades old and have focused solely on enrollment to treatment trials, which does not reflect the willingness of patients to contribute to other elements of clinical research. We determined inclusive, contemporary estimates of clinical trial participation for adults with cancer using a national sample of data from the Commission on Cancer (CoC). METHODS The data were obtained from accreditation information submitted by the 1,200 CoC programs, which represent more than 70% of all cancer cases diagnosed in the United States each year. Deidentified, institution-level aggregate counts of annual enrollment to treatment, biorepository, diagnostic, economic, genetic, prevention, quality-of-life (QOL), and registry studies were examined. Overall, study-type estimates for the period 2013-2017 were estimated. Multiple imputation by chained equations was used to account for missing data, with summary estimates calcul
Source: ascopubs.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 12Systematic review of adoption, reporting and impact of health-related quality of life in phase III non-inferiority trials of systemic oncology treatments - 1 month(s) ago
Quality of life (QoL) assessment and patient-reported outcomes appear to be crucial in the rationale and interpretation of non-inferiority (NI) trials. The aim of this study was to assess the inclusion of QoL among endpoints in phase III NI oncology trials and the relevance of QoL results in the reporting and interpretation of these studies.
Source: www.ejcancer.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 30
PURPOSE Comorbid insomnia and cancer-related cognitive impairment (CRCI) are experienced by up to 26% of individuals diagnosed with cancer. This study examined the efficacy and durability of cognitive behavioral therapy for insomnia (CBT-I) on perceived CRCI in cancer survivors. METHODS Atlantic Canadian cancer survivors with insomnia and CRCI were randomly assigned to receive seven weekly virtual CBT-I sessions (n = 63) or placed in a waitlist control group (n = 69) to receive treatment after the waiting period. Participants completed assessments at baseline, 1 month (mid-treatment), and 2 months (post-treatment). Age- and education-adjusted mixed-effects models using intention-to-treat principles assessed change at post-treatment. Data from both groups were then pooled to assess the durability of effects at 3 and 6 months. A mediation analysis examined whether change in insomnia symptoms mediated the effect of CBT-I on cognitive outcomes. RESULTS The mean age of the sample was 60 yea
Source: ascopubs.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 5
This Review summarizes current best practices for risk stratification, clinical assessment, and selection of risk reduction interventions for falls in community-dwelling older adults.
Source: jamanetwork.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 70Real-World Database Studies in Oncology: A Call for Standards - 2 month(s) ago
Real-world data (RWD), the data relating to patient health status and routinely collected in the delivery of health care, can provide critical evidence about care and outcomes across the cancer continuum. When analyzed using rigorous methods, RWD can address a number of important questions that are not practical, feasible, or ethical to address with clinical trials. This important advantage of RWD is also a limitation, namely, what is captured in real-world databases reflects the observed experiences,
Source: ascopubs.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 70Real-World Database Studies in Oncology: A Call for Standards - 2 month(s) ago
Real-world data (RWD), the data relating to patient health status and routinely collected in the delivery of health care, can provide critical evidence about care and outcomes across the cancer continuum. When analyzed using rigorous methods, RWD can address a number of important questions that are not practical, feasible, or ethical to address with clinical trials. This important advantage of RWD is also a limitation, namely, what is captured in real-world databases reflects the observed experiences,
Source: ascopubs.orgCategories: General Medicine News, Hem/OncsTweet
Do goals of care documentation reflect the conversation? Evaluating conversation-documentation accuracy. https://t.co/mGI3SFil0e @AmerGeriatrics @AGSJournal @DukeGeriatrics #Geriatrics #PallOnc #GeriOnc #PalliativeCare https://t.co/rMl01YYRwP