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Mashup Score: 2
Spread through air spaces (STAS) consists of lung cancer tumor cells that are identified beyond the edge of the main tumor in the surrounding alveolar parenchyma. It has been reported by meta-analyses to be an independent prognostic factor in the major histologic types of lung cancer, but its role in lung cancer staging is not established.
Source: www.jto.orgCategories: General Medicine News, Oncologists1Tweet
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Mashup Score: 13
The goal of surgical resection is to completely remove a cancer; it is useful to have a system to describe how well this was accomplished. This is captured by the residual tumor (R) classification, which is separate from the TNM classification that describes the anatomic extent of a cancer independent of treatment. The traditional R-classification designates as R0 a complete resection, as R1 a macroscopically complete resection but with microscopic tumor at the surgical margin, and as R2 a resection that leaves gross tumor behind.
Source: www.jto.orgCategories: General Medicine News, Onc News and JournalsTweet-
This paper represents a comprehensive review of evidence regarding R categories & the descriptors thereof. W/the same overall framework & descriptors in the 9th edition, refinements to the descriptors should facilitate application & further research.https://t.co/Pqc8zM7djK #IASLC https://t.co/M8MHFkSSq3
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Mashup Score: 18
The TNM classification of lung cancer is periodically revised. The International Association for the Study of Lung Cancer collected and analyzed a new database to inform the forthcoming ninth edition of the TNM classification. The results are herewith presented.
Source: www.jto.orgCategories: General Medicine News, Oncologists1Tweet-
The IASLC collected/analyzed a new database of pts w/#lungcancer to inform the forthcoming 9th edition of the classification of LC based on its anatomic extent (TNM), which is periodically revised. The results concerning the LC stage groups are here: https://t.co/8TnRyu4mwF #LCSM https://t.co/mVaH6xkQMo
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Mashup Score: 7Prevalence of EGFR Mutations in Patients With Resected Stages I to III NSCLC: Results From the EARLY-EGFR Study - 4 month(s) ago
There is limited literature on the prevalence of EGFR mutations in early stage NSCLC. EARLY-EGFR (NCT04742192), a cross-sectional study, determined the prevalence of EGFR mutations in early stage NSCLC.
Source: www.jto.orgCategories: General Medicine News, Oncologists1Tweet-
There is limited literature on the prevalence of EGFR mutations in early-stage NSCLC. EARLY-EGFR (NCT04742192), a cross-sectional multi-region study, determined the prevalence of EGFR mutations in early-stage NSCLC. Read about the results here: https://t.co/uAn3tBLuCz #LCSM https://t.co/tmCb5GH9n5
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Mashup Score: 5
The eighth edition of the TNM classification of pleural mesothelioma (PM) saw substantial changes in T and N components and stage groupings. The International Association for the Study of Lung Cancer collected data into a multinational database to further refine this classification. This ninth edition proposal incorporates changes proposed in the clinical (c)T component but not the pathologic T component, to include size criteria, and further refines TNM stage groupings for PM.
Source: www.jto.orgCategories: General Medicine News, Oncologists1Tweet-
These authors/members of the Staging & Prognostic Factors Committee of the Advisory Boards & Participating Institutions present their proposal for the revision of the TNM stage groupings in the 9th edition of the TNM Classification for Pleural Mesothelioma:https://t.co/09x1VOTikC https://t.co/gSov82Jr63
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Mashup Score: 2
The use of tumor-informed circulating tumor DNA (ctDNA) testing in early-stage patients before surgery is limited mainly due to restricted tissue access and extended turnaround times. This study aimed to evaluate the clinical value of a tumor-naïve, methylation-based cell-free DNA assay in a large cohort of patients with resected non-small cell lung cancer (NSCLC).
Source: www.jto.orgCategories: General Medicine News, Oncologists1Tweet-
This study aimed to evaluate the clinical value of a tumor-naïve, methylation-based cell-free DNA assay in a large cohort of patients with resected #NSCLC. Read more about the findings here: https://t.co/o4NdaSKtHy #LCSM https://t.co/jfhRsuerCv
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Mashup Score: 3Lung Cancer in Ghana - 4 month(s) ago
Ghana is a country in West Africa and abuts the Gulf of Guinea and the Atlantic Ocean to the south. It is bordered to the northwest and north by Burkina Faso, to the east by Togo, to the south by the Atlantic Ocean, and to the west by Côte d’Ivoire (Fig. 1). The country covers an area of 239,567 km2 (92,497 sq mi), spanning diverse biomes that range from coastal savannas to tropical rainforests, and has more than 30 million inhabitants as reported by the last population and housing census in 2021.
Source: www.jto.orgCategories: General Medicine News, Oncologists1Tweet-
For July Editor's Choice, explore the epidemiology, staging, screening, and management of #ungcancer in Ghana in this issue of Lung Cancer Worldwide: https://t.co/d3b48RqPKv #LCSM https://t.co/w2UFu0ggJ7
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Mashup Score: 3Global Burden of Lung Cancer Attributable to Household Fine Particulate Matter Pollution in 204 Countries and Territories, 1990 to 2019 - 4 month(s) ago
Household particulate matter (PM) air pollution is substantially associated with lung cancer. Nevertheless, the global burden of lung cancer attributable to household PM2.5 is still uncertain.
Source: www.jto.orgCategories: General Medicine News, Oncologists1Tweet-
Household particulate matter (PM) air pollution is substantially associated w/#lungcancer. However, the prevalence of lung cancer attributable to household PM2.5 has declined from 1990 to 2019 owing to a concurrent decline in household PM2.5 exposure:https://t.co/0OGg4S4cgG #LCSM https://t.co/NLl4Nai4dV
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Mashup Score: 1Ficonalkib (SY-3505) in Advanced ALK-Positive NSCLC: A Multicenter, Open-Label, Single-Arm, Phase 1/2 Study - 5 month(s) ago
Treatment options for second-generation (2nd-gen) ALK tyrosine kinase inhibitor (TKI)-resistant patients are limited. We evaluated the safety, pharmacokinetics, and efficacy of ficonalkib (SY-3505), a third-generation (3rd-gen) ALK TKI, in patients with advanced ALK-positive non-small cell lung cancer.
Source: www.jto.orgCategories: General Medicine News, Oncologists1Tweet-
Treatment options for 2nd-gen ALK TKI-resistant pts are limited. Authors evaluated safety, pharmacokinetics & efficacy of ficonalkib (SY-3505), a 3rd-gen ALK TKI, in pts w/advanced ALK-positive #NSCLC. Ficonalkib (SY-3505) was well tolerated in some pts. https://t.co/UVStndAqXU https://t.co/TIStHvdK7T
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Mashup Score: 13
This study analyzed all metastatic categories of the current tumor, node, and metastasis (TNM) classification of non-small cell lung cancer to propose modifications of the M component in the next edition (9th) of the classification.
Source: www.jto.orgCategories: General Medicine News, Onc News and JournalsTweet-
This study analyzed all metastatic categories of the TNM classification of #NSCLC to propose modifications of the M component in the 9th edition, the data validates the 8th edition M1a & M1b categories. Read more including a proposal re: the M1c category: https://t.co/YyN6PyDF4z https://t.co/4ch3qq5ks3
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A study focused on whether STAS could be a useful add'l histologic descriptor to supplement existing ones of VPI & LVI. The data supports the recommendation to include STAS as histologic descriptor for the 9th Ed. of the TNM Classification of #lungcancer.https://t.co/gZuRE4WPTl https://t.co/ZiMzfcaBAP